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Frontiers in Computational Chemistry: Volume 6
  • Language: en
  • Pages: 310

Frontiers in Computational Chemistry: Volume 6

Frontiers in Computational Chemistry presents contemporary research on molecular modeling techniques used in drug discovery and the drug development process: computer aided molecular design, drug discovery and development, lead generation, lead optimization, database management, computer and molecular graphics, and the development of new computational methods or efficient algorithms for the simulation of chemical phenomena including analyses of biological activity. The sixth volume of this series features these six different perspectives on the application of computational chemistry in rational drug design: 1. Computer-aided molecular design in computational chemistry 2. The role of ensemble conformational sampling using molecular docking & dynamics in drug discovery 3. Molecular dynamics applied to discover antiviral agents 4. Pharmacophore modeling approach in drug discovery against the tropical infectious disease malaria 5. Advances in computational network pharmacology for Traditional Chinese Medicine (TCM) research 6. Progress in electronic-structure based computational methods: from small molecules to large molecular systems of biological significance

Deconstructing Development Discourse
  • Language: en
  • Pages: 320

Deconstructing Development Discourse

Andrea Cornwall is Professor of Anthropology and Development in the School of Global Studies at the University of Sussex. --

Metrópoles Latino-americanas
  • Language: pt-BR
  • Pages: 513

Metrópoles Latino-americanas

Esta obra, genuinamente coletiva, é uma pequena parte de um processo maior de construção do pensamento geográfico dentro do âmbito acadêmico, cuja missão é problematizar aspectos da realidade Latino-Americana a partir do projeto da Universidade Federal da Integração Latino-Americana – UNILA, especialmente no interior do curso de Geografia. Este livro nasce dos debates sobre as Metrópoles na América Latina feitos no decorrer disciplina que levou o mesmo nome e no trabalho de campo realizado em Buenos Aires pelos geógrafos e geógrafos em formação e profissionais de outras áreas, também em formação, que acompanharam o curso e o campo no segundo semestre do ano de 2014. Com diferentes perspectivas geográficas, esta obra traz textos de brasileiros, uruguaios e venezuelanos que compartilham o projeto de refletir sobre as principais questões da América Latina, no caso deste livro, as principais questões que envolvem o espaço metropolitano da cidade de Buenos Aires.

Uniting Knowledge Integrated Scientific Research For Global Development
  • Language: en
  • Pages: 1849
Standards for the Management of Open Fractures of the Lower Limb
  • Language: en
  • Pages: 97

Standards for the Management of Open Fractures of the Lower Limb

The Standards for the Management of Open Fractures of the Lower Limb details the optimal treatment for patients with these challenging injuries. Drawing on an extensive review of the published evidence and their personal experience, the authors set out each stage of the management pathway, including what to do if complications arise. Of relevance to pre-hospital, emergency room and hospital clinicians, each chapter contains key recommendations for the standards of care that should be delivered, with practical advice on how to achieve these and the evidence that supports them Containing important new guidance for getting the best outcomes, the Standards are an essential reference for orthopaedic, plastic surgery, emergency medicine, and rehabilitation specialists who treat these injuries as well for those who plan and commission trauma care Endorsed by the Councils of the British Association of Plastic, Reconstructive and Aesthetic Surgeons and the British Orthopaedic Association, The Standards for the Management of Open Fractures of the Lower Limb replaces previous guidelines in the UK and will have worldwide relevance

Cancer Metastasis Through the Lymphovascular System
  • Language: en
  • Pages: 785

Cancer Metastasis Through the Lymphovascular System

This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the im...

Phenotypic Drug Discovery
  • Language: en
  • Pages: 273

Phenotypic Drug Discovery

Phenotypic drug discovery has been highlighted in the past decade as an important strategy in the discovery of novel medical entities. This book aims to equip researchers with a thought-provoking guide to the application and development of contemporary phenotypic drug discovery for clinical success.

Soccer World - Summer Edition 2010
  • Language: it
  • Pages: 333

Soccer World - Summer Edition 2010

  • Type: Book
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  • Published: 2011-04-20
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  • Publisher: Lulu.com

SOCCER WORLD Summer Edition 2010 l'unico volume semestrale statistico sul calcio internazionale prodotto in Italia. Nasce per colmare una persistente lacuna nel settore della editoria calcistica. Il libro prende in considerazione più di 25 campionati tra europei, nord-sudamericani ed asiatici con particolare attenzione al calciomercato, organici delle squadre minuziosamente aggiornati, disposizioni in campo dei giocatori, onorificenze e analisi statistica della stagione 2009/10 con tutti i risultati che servono a comprenderne l'andamento. Esaminate più di 400 formazioni con dati anagrafici di oltre 16.000 calciatori. Una carrellata di informazioni che permette una visione globale, completa ed aggiornata della stagione calcistica internazionale!

Advances in Bioinformatics and Computational Biology
  • Language: en
  • Pages: 159

Advances in Bioinformatics and Computational Biology

This book constitutes the refereed proceedings of the Brazilian Symposium on Bioinformatics, BSB 2021, held in November 2021. Due to COVID-19 pandemic the conference was held virtually The 10 revised full papers and 5 short papers were carefully reviewed and selected from 28 submissions. The papers address a broad range of current topics in computational biology and bioinformatics.

Intelligent Systems
  • Language: en
  • Pages: 682

Intelligent Systems

The two-volume set LNAI 13653 and 13654 constitutes the refereed proceedings of the 11th Brazilian Conference on Intelligent Systems, BRACIS 2022, which took place in Campinas, Brazil, in November/December 2022. The 89 papers presented in the proceedings were carefully reviewed and selected from 225 submissions. The conference deals with theoretical aspects and applications of artificial and computational intelligence.