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Cellular Senescence and Aging
Cellular Senescence and Aging, Volume 181 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as assessing polyglutamine tract aggregation in the nematode Caenorhabditis elegans, Generation of glial cell-derived neurotrophic factor (gdnf) morphants in zebrafish larvae by cerebroventricular microinjection of vivo morpholino, Methods for detection of mitochondrial reactive oxygen species in senescent cells, Assessment of cell cycle progression and mitotic slippage by videomicroscopy, The original colorimetric method to detect cellular senescence, and more.Additional sections cover Assessing microbiota ...
Radiation Oncology and Radiotherapy Part B
Radiation Oncology and Radiotherapy, Part B, Volume 174 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics including CT-assisted focal irradiation of tumors in mice, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Cytofluorometric characterization of the lymphoid compartment of irradiated tumors, Cytofluorometric characterization of the myeloid compartment of irradiated tumors, Mass cytometry to characterize the immune infiltrate of irradiated tumors, Characterization of the immune infiltrate in irradiated mouse tumor by multiplex i...
Radiation Oncology and Radiotherapy, Part A
Radiation Oncology and Radiotherapy, Part A, Volume 172 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including DNA damage quantification by the COMET assay, Immunofluorescence microscopy-assisted quantification of ATM and ATR activation in irradiated cells, Immunoblotting-based characterization of the DNA damage response, Assessment of lipid peroxidation in irradiated cells, A simple method to assess clonogenic survival of irradiated cancer cells, Quantification of beta-galactosidase activity as a marker of radiation-driven cellular senescence, Cytofluorometric assessment of cell cycle progress...
Tesla Carbon Pigs, Climate Change, Environmental Equity and Liberal Democracy
Read how the typical TESLA electric vehicle driver is more affluent than the average citizen and consumes considerably more carbon to live their comfortable lives at their first or second home with their private clubs, take-out food, household staff, extensive vacations, etc. The vow of poverty to immediately aid our environment is not in the cards for these carbon pigs, or for the rest of us for that matter. Most of us fall short between our personal consumption habits and our public persona expressing concern for our environment. Read how amazon prime is unsustainable at any speed of delivery as other delivery options, albeit slower, are already in your neighborhood. Read about various str...
The Electric Vehicle Revolution
A Fascinating Look at the 5 Leading Personalities Driving the Transition to Electric Vehicles and Reinventing the Auto Industry The leading car manufacturing firms have all essentially pledged to transition from traditional carbon dioxide-emitting vehicles to battery-powered electric vehicles. Tesla has led the way to date, recently producing its three millionth car since its first sale in 2009. General Motors has committed to carbon neutrality in its global products and operations by 2040. Honda has committed to carbon neutrality as well as zero traffic collision fatalities by 2050. These are ambitious and noble goals, yet they will take a supreme transformation to achieve. In The Electric ...
Cancer Immunotherapy Principles and Practice, Second Edition
Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory proces...
Carcinogen-Driven Mouse Models of Oncogenesis
Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more. Ot...
Brain Energy
Nautilus Book Awards Gold Winner in Psychology/Mental & Emotional Well-Bein Foreword INDIES Book of the Year Finalist in Health 2023 Next Generation Indie Book Awards Finalist This is the book that will forever change the way we understand and treat mental health. If you or someone you love is affected by mental illness, it might change your life. We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about ...
