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Handbook on Longevity Medicine
  • Language: en
  • Pages: 428

Handbook on Longevity Medicine

This handbook is the next volume in the series of the scientific and educational publications of the European Society of Preventive, Regenerative and Anti-Aging Medicine. To promote the development of the science and practice of anti-ageing and active longevity, ESAAM has published in 2023 the Handbook of Anti-Aging Medicine. This cornerstone book was devoted to main theoretical issues in combating the mechanisms of aging. Current handbook provides the basics of practical life extension protocols. Leading specialists in regenerative and longevity medicine presented their valuable recommendations. Special attention is paid to the fundamental principles of the longevity clinic, as well as prac...

Discourses and Narrations in the Biosciences
  • Language: en
  • Pages: 302

Discourses and Narrations in the Biosciences

Discourses and Narrations in the Biosciences investigates the forms of writing in which scientific claims are formulated and announced. Argumentative strategies, compositional rules, and figurative expressions in communication and narrativization of scientific knowledge are the focus of interdisciplinary contributions by humanities and science scholars. The first part of the book, dedicated to 'Rhetorical and Epistemological Aspects of Science Writing', addresses how scientific pursuits and methods feed into multi-level texts that generate responses within science, society, and culture. The second part, entitled 'Bioscientific Discourses and Narrations', examines popularisations and fictionalizations of science in relation to diversity, deviancy, ageing, illness, reproduction, the evolution of humankind, mathematical models of biomedical systems, and the myth of the heroic scientist. Assessing the narrative impetus and command of literary and meta-discoursive strategies shown by contemporary science writers enhances understanding of the methods and conventions through which the biosciences produce knowledge.

Basic Biology and Clinical Impact of Immunosenescence
  • Language: en
  • Pages: 323

Basic Biology and Clinical Impact of Immunosenescence

  • Type: Book
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  • Published: 2003-05-01
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  • Publisher: Elsevier

Ageing is of perennial interest as a universal feature in all human societies. The genetic background and biochemical bases of ageing processes are currently being revealed in unprecedented detail. It is emerging that one of the main hurdles to be overcome in achieving a long and healthy lifespan is the maintenance of a properly functioning immune system. The main cause of death in people who have achieved "successful ageing" (which mostly means not having succumbed to cancer or cardiovascular disease) is infectious disease, caused by immunosenescence. This book contains chapters by many of the leaders in the field of immune-related issues in ageing and remediation.

The Neuroendocrine Immune Network in Ageing
  • Language: en
  • Pages: 456

The Neuroendocrine Immune Network in Ageing

  • Type: Book
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  • Published: 2004-07-24
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  • Publisher: Elsevier

The book describes the mechanisms involved in the maintenance of neuroendocrine-immune interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability. The capacity of some hormones or nutritional factors in restoring and remodelling the neuroendocrine-immune response during ageing is reported presenting possible new anti-ageing strategies in order to reach healthy ageing and longevity.

Centenarians
  • Language: en
  • Pages: 182

Centenarians

  • Type: Book
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  • Published: 2019-08-05
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  • Publisher: Springer

This state-of-the-art review on longevity focuses on centenarians, studied as a model of positive biology. The extraordinary rise in the elderly population in developed countries underscores the importance of studies on ageing and longevity in order to decrease the medical, economic and social problems associated with the increased number of non-autonomous individuals affected by invalidating pathologies. Centenarians have reached the extreme limits of human life span. Those in relatively good health, who are able to perform their routine daily tasks, are the best examples of extreme longevity, representing selected individuals in which the appearance of major age-related diseases – includ...

Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan
  • Language: en
  • Pages: 204

Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan

  • Type: Book
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  • Published: 2021-06-15
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  • Publisher: MDPI

People around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050, there will be 434 million people in this age group worldwide. In addition, the pace of aging of the world population is also increasing. However, there is not enough evidence to show that older people have better health than their parents. While rates of severe disability have declined over the past 30 years (but only in high-income countries), there have been no significant changes in mild to moderate disability over the same period of time. Indeed, the increase in the duration of life (lifespan) does not coincide with the increase in the duration of health (healthspan), that is, the period of life free from serious chronic diseases and disabilities. Therefore, the identification of the factors that predispose to a long and healthy life, as discussed in the papers of this book, is of enormous interest for translational medicine.

Human Aging
  • Language: en
  • Pages: 384

Human Aging

Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. - Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging - Offers the ability to access cross-sectional knowledge more easily - Written by expert researchers in biogerontology who are actively involved in various fields within aging research

Immunology of Aging
  • Language: en
  • Pages: 411

Immunology of Aging

The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.

Cytokine Gene Polymorphisms in Multifactorial Conditions
  • Language: en
  • Pages: 489

Cytokine Gene Polymorphisms in Multifactorial Conditions

  • Type: Book
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  • Published: 2006-06-21
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  • Publisher: CRC Press

The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphism

Identities Across Media and Modes
  • Language: en
  • Pages: 392

Identities Across Media and Modes

  • Type: Book
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  • Published: 2009
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  • Publisher: Peter Lang

The recognition that identity is mutable, multi-layered and subject to multiple modes of construction and de-construction has contributed to problematizing the issues associated with its representation in discourse, which has recently been attracting increasing attention in different disciplinary areas. Identity representation is the main focus of this volume, which analyses instances of multimedia and multimodal communication to the public at large for commercial, informative, political or cultural purposes. In particular, it examines the impact of the increasingly sophisticated forms of expression made available by the evolution of communication technologies, especially in computer-mediate...