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Environmental and Technology Policy in Europe
This book contains six studies on various national environmental policies and environment -oriented technology policy systems in Austria, Denmark, Germany, the Netherlands, Spain, and the United Kingdom, sandwiched between this introductory and a concluding chapter. These studies were conducted as part of the ENVINNO research project, "Towards an Integration of Environmental and Ecology-Oriented Technology Policy: Stimulus and Response in Environment Related Innovation Networks", which formed part of the Targeted Social and Economic Research (TSER) Programme of Directorate-General XII of the European Commission, now 1 Directorate-General for Research. We like to thank Mrs. Genevieve Zdrojews...
Drinking Water Supply and Agricultural Pollution
Agricultural pollution (with nitrates and pesticides) is one of the biggest threats to drinking water resources. At many places regional and local water authorities, together with the water supply industry, are involved in preventive action aimed at farming practices. Three national case studies (Germany, The Netherlands, and the United Kingdom) analyse these efforts within the context of problematical national agricultural policy and the need to implement EU directives on water quality. Additional case studies cover the role of the European Union, while the same problem in a different setting is analysed for the United States. The central question of how national and European governments can reinforce the control capacity of the actors at the regional and local level, is treated from the theoretical perspective of the policy network approach.
Drinking Water Supply and Agricultural Pollution
Agricultural pollution (with nitrates and pesticides) is one of the biggest threats to drinking water resources. At many places regional and local water authorities, together with the water supply industry, are involved in preventive action aimed at farming practices. Three national case studies (Germany, The Netherlands, and the United Kingdom) analyse these efforts within the context of problematical national agricultural policy and the need to implement EU directives on water quality. Additional case studies cover the role of the European Union, while the same problem in a different setting is analysed for the United States. The central question of how national and European governments can reinforce the control capacity of the actors at the regional and local level, is treated from the theoretical perspective of the policy network approach.
Role of Tyrosine Kinases in Gastrointestinal Malignancies
The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy. Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.
Colorectal Cancer Liver Metastases
Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the lat...
Gastrointestinal Malignancies
This book comprehensively summarizes the current state of knowledge on malignancies of the gastrointestinal tract. Dedicated organ-based chapters evaluate current treatments and management and provide information on incidence, etiology and biological characteristics. The state of the art in the radiologic and endoscopic staging of gastrointestinal malignancies is described, and guidance is offered on the role of interventional radiology and interventional gastroenterology in the treatment of these challenging tumors. In addition, the book explores novel and evolving treatments, including personalized systemic therapy and minimally invasive surgical and radiology techniques, and addresses patient-reported outcomes and survivorship challenges. It closes by discussing animal models of gastrointestinal malignancies and examining the significance of the Ras superfamily of GTPases. It will be of benefit to all surgeons, oncologists and other specialists who treat these malignancies, as well as to trainees looking to increase their understanding of the field.
Medifocus Guidebook On: Colorectal Cancer
The MediFocus Guidebook on Colorectal Cancer is the most comprehensive, up-to-date source of information available. You will get answers to your questions, including risk factors of Colorectal Cancer, standard and alternative treatment options, leading doctors, hospitals and medical centers that specialize in Colorectal Cancer, results of the latest clinical trials, support groups and additional resources, and promising new treatments on the horizon. This one of a kind Guidebook offers answers to your critical health questions including the latest treatments, clinical trials, and expert research; high quality, professional level information you can trust and understand culled from the latest peer-reviewed journals; and a unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks. This Guidebook was updated on January 29, 2012.
Drug Delivery in Oncology, 3 Volume Set
In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleot...
Drug Delivery in Oncology
In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleot...
Colorectal Cancer Biology
Colorectal cancer is a common disease, affecting millions worldwide and represents a global health problem. Effective therapeutic solutions and control measures for the disease will come from the collective research efforts of clinicians and scientists worldwide. This book presents the current status of the strides being made to understand the fundamental scientific basis of colorectal cancer. It provides contributions from scientists, clinicians and investigators from 20 different countries. The four sections of this volume examine the evidence and data in relation to genes and various polymorphisms, tumor microenvironment and infections associated with colorectal cancer. An increasingly better appreciation of the complex inter-connected basic biology of colorectal cancer will translate into effective measures for management and treatment of the disease. Research scientists and investigators as well as clinicians searching for a good understanding of the disease will find this book useful.
