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Membrane Glycoproteins
Membrane Glycoproteins: A Review of Structure and Function deals with membrane glycoproteins found in biological systems. The book describes the structure and biosynthesis of the glycoproteins in relation to known or postulated functions in membranes. The text opens with an introduction and a topic on detection and distribution of membrane glycoproteins. The book then notes that the isolation of membrane glycoproteins brought by the progress in research and technology of membrane solubilization and purification of the soluble components is now possible. Discussion is also directed to glycoproteins as being integral components of intracellular membranes, and not just located on cell surfaces....
Glycoproteins I
Part I covers modern advances in the determination ofglycoprotein structure and in the biosynthesis of mammalian,bacterial, yeast, plant and insect glycoproteins. There are alsotwo chapters on functional aspects (glycoprotein hormones andcollagens).The content of the volume is very comprehensive in that, mostcontributors have focussed on discussing, in depth, the wealthof most recent advances in their field, and referring to previousreviews of older work for background information. This method caneffectively produce a very wide subject coverage in a smallernumber of chapters/volumes.The volume is an importantinformation source for all glycobiologist researchers (seniorinvestigators, post-doctoral fellows and graduate students), andas a good, comprehensive, reference text for scientists working inthe life sciences.
Essentials of Glycobiology
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
The Biology of Glycoproteins
This book is in many ways a sequel to The Biochemistry ojGlycoproteins and Proteoglycans. The enormous recent progress in understanding the biological roles of glycoproteins has prompted the present volume. The reasons for studying glycoproteins have multiplied, and in the present volume the roles played by glycoproteins are explored in a variety of biological situations. The first two chapters describe molecules involved in cell-substratum and cell-cell interactions in a broad sense, and also focus on recent progress in identifying specific attachment molecules. Our understanding of how normal processes, such as cellular differentiation and tissue organization, are regulated is dependent on...
Recombinant Glycoproteins
Zusammenfassung: This detailed volume explores the production and purification of glycoproteins for therapeutic use or basic research, as well as the necessary in-depth understanding of cellular and acellular systems available for these purposes, their advantages and disadvantages, and considerations for choosing the most appropriate system for the desired application. Beginning with chapters on viral-encoded glycoproteins and those found in other pathogens, the book continues by examining the production of mammalian glycoproteins, the analysis of glycoprotein content, cell-free synthesis of glycoproteins and considerations for production and purification of glycoproteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to the respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Recombinant Glycoproteins: Methods and Protocols provides a wide range of guidelines for studying these vitally important proteins
Glycoproteins II
Part II of this excellent work covers proteoglycans and mucins and deals with many more examples of glycoprotein function. It also covers glycoproteins from four more species (slime mold, snails, fish, batracians).The content of the volume is very comprehensive in that most contributors are focussed on discussing, in depth, the wealth of most recent advances in their field, referring to previous reviews of older work for background information. This method effectively produces a very wide subject coverage in a smaller number of chapters/volumes. The volume is an important information source for all glycobiologist researchers (senior investigators, post-doctoral fellows and graduate students), and as a good, comprehensive, reference text for scientists working in the life sciences.
Functional and Structural Proteomics of Glycoproteins
It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.
Glycoproteins
The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably concerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a background know ledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with...
The Biochemistry of Glycoproteins and Proteoglycans
Although glycoproteins and proteoglycans have been a subject of re search for many years, it is only during the last five or so years that they have aroused the interest of a very broad cross section of investigators in the biological sciences. The reason for this expanded interest in these molecules is simple: not only are glycoproteins and proteoglycans ubiq uitous, but many are molecules with well-defined and important biological functions. The list of molecules that fall into this category grows daily; interferon, immunoglobulins, certain hormones, many cell surface recep tors, and viral coat proteins are but a few examples. Thus, investigators with interests as diverse as viral replicat...
Functional and Structural Proteomics of Glycoproteins
It has been predicted that nearly half of all human proteins are glycosylated indicating the significance of glycoproteins in human health and disease. For example, the glycans attached to proteins have emerged as important biomarkers in the diagnosis of diseases such as cancers and play a significant role in how pathogenic viruses gain entry into human cells. The study of glycoproteins has now become a truly proteomic science. In the last few years, technology developments including in silico methods, high throughput separation and detection techniques have accelerated the characterization of glycoproteins in cells and tissues. Glyco-engineering coupled to rapid recombinant protein production has facilitated the determination of glycoprotein structures key to exploring and exploiting their functional roles. Each chapter in this volume is written by experts in the field and together provide a review of the state of the art in the emerging field of glycoproteomics.
