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This book comprehensively reviews the association of homocysteine metabolism with the etiology of various human disorders. The well-defined chapters embedded the central and peripheral effects of homocysteine metabolism intricately related with cardiovascular, neurodegenerative, metabolic, and autoimmune disorders. Further, it discusses the mechanisms of perturbance of cellular proteostasis by elevated homocysteine levels and provides a comprehensive account of pathophysiological consequences and clinical implications of homocysteine-containing proteins. The book also reviews association of genetic variants of homocysteine metabolic genes with type 2 diabetes mellitus and obesity. It also describes the molecular mechanism of hyperhomocysteinemia in the negative/feedback regulation of neural stem cell proliferation and alterations in DNA methylation. Taken together, it summarizes the mechanisms of hyper homocysteinemia-induced endothelial dysfunction and physiological functions of hydrogen sulfide as the protective agent.
Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural compounds from their plant sources with the goal of treating specific diseases. Bioactive Phytochemicals: Drug Discovery to Product Development explores the scope and approaches of drug discovery from natural products. Chapters in the book cover information about the cultivation, collection and processing of medic...
Several plant bioactives or plant-derived therapeutic molecules have been used against life-threatening diseases and their nanoparticle-mediated delivery greatly improves therapeutic efficacy. Advances in Phytonanotechnology for Treatment of Various Diseases aims to describe past and recent advances achieved in the field of phytonanotechnology. The chapters of this book provide thorough knowledge of medicinal plants, plant bioactives, plant extract-based nanoparticle synthesis, delivery of plant bioactives through nanoparticles, and their therapeutic activity against life-threatening diseases. This book focuses on the therapeutic activity of phytocomponents present in plants from diverse fam...
Obesity and Diabetes: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Obesity and Diabetes: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Obesity and Diabetes: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Contents: Eco-system, Form and Processes: Conceptual Framework, Process of Urbanisation, Migration Regional Development and Territorial Planning, Concept of Geo-ecological Processes and Geo-spatial Paradigm, Concept of Work and Workers in Global Perspective, Concept of Perception and Source of Confusion in Environmental Research, Concepts and Issues of Environmental Mapping, Concept of Settlement, Domicile and Residence in Law Point of View, Geomorphic Environment, Flood Hazard and Its Management: A Case Study of Jaunpur District, U.P., Environmental Scenario of Chitrakut Upland; Its Past, Present and Future, Profile of India s Population on the Threshold of the 21st Century, Role of Non-polluting Renewable Energy Systems in Human Resource Development, Recycling of Wastes for Human Resource Development, Environmental Assessment of Ganga Basin, Stream Segmentation and Bifurcation Ratio (Rb) of Pachmarhi Hills, M.P.