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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers G protein coupled receptors, and includes chapters on such topics as GPCR modelling, interactions with other molecules, virtual screening and GPCR activation. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers G protein coupled receptors - Contains chapters on such topics as GPCR modelling, interactions with other molecules, virtual screening and GPCR activation
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Wastewater Treatment: Recycling, Management, and Valorization of Industrial Solid Wastes bridges the gap between the theory and applications of wastewater treatments, principles of diffusion, and the mechanism of biological and industrial treatment processes. It presents the practical applications that illustrate the treatment of several types of data, providing an overview of the characterization and treatment of wastewaters, and then examining the different biomaterials and methods for the evaluation of the treatment of biological wastewaters. Further, it considers the various types of industrial wastewater treatment, separation, and characterization of industrial wastewater. The book serves as a valuable resource for practicing engineers and students who are interested in the field of wastewater treatment. Features: Presents the latest technologies in water treatment, including nanomaterials for industrial wastewater Covers different treatments for various industrial wastewaters, including chemical and pharmaceutical waste Includes forward-thinking analysis including conclusions and recommendations for water reuse programs
G protein-coupled receptors (GPCRs) constitute the largest superfamily of cell surface receptors that regulate a variety of cell functions. Over the past few decades great progress has been made in defining the roles of intracellular trafficking in controlling the functionality of the receptors as well as in the development of various human diseases. This volume of Progress in Molecular Biology and Translational Science reviews the recent understanding of GPCR trafficking regulators and molecular mechanisms. - Written by future leaders in the pain field - Covers a wide range of targets - Contains provocative ideas about GPCR trafficking
In Intoxicating Shanghai, Paul Bevan explores the work of a number of Chinese modernist figures in the fields of literature and the visual arts, with an emphasis on the literary group the New-sensationists and its equivalents in the Shanghai art world, examining the work of these figures as it appeared in pictorial magazines. It undertakes a detailed examination into the significance of the pictorial magazine as a medium for the dissemination of literature and art during the 1930s. The research locates the work of these artists and writers within the context of wider literary and art production in Shanghai, focusing on art, literature, cinema, music, and dance hall culture, with a specific emphasis on 1934 – ‘The Year of the Magazine’.
This volume covers topics such as the structure and identification of functional domains of G proteins, and activation of G proteins by receptors or other regulators. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences.
This is the first of a two-volume set that constitutes the refereed proceedings of the Second International Conference on Usability and Internationalization, UIHCII 2007, held in Beijing, China in July 2007. The papers of this first volume cover HCI and culture and are organized in topical sections on cross-cultural design, internationalization and intercultural usability, as well as user studies.
This volume of Current Topics in Membranes focuses on adrenergic receptor biology, beginning with a review of past successes and historical perspectives then further discussing current general trends in adrenic receptor studies in various contexts. This publication also includes discussions of the role and relationship of adrenergic receptors to different systems and diseases, establishing adrenergic receptor biology as a needed, practical reference for researchers.
Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways. How do GPCR signalling complexes get assembled to generate such specificity? In order to answer this question, we need to understand how receptors and their signalling partners are synthesized, folded and quality-controlled in order to generate functional proteins. Then, we need to understand how each partner of the signalling complex is selected to join a complex, and what makes this assembly possible. GPCRs are known to be able to function as oligomers, what drives the assembly into oligomers and what will be the effects of such organization on specificity and efficacy of signal transduction. Once the receptor complexes are assembled, they need to reach different locations in the cell; what drives and controls the trafficking of GPCR signalling complexes. Finally, defects in synthesis, maturation or trafficking can alter functionality of GPCRs signalling complexes; how can we manipulate the system to make it function normally again? Pharmacological chaperones may just be part of the answer to this question.