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Breakthroughs in Space Life Science Research
This last volume of the SpringerBriefs in Space Life Sciences series is setup in 5 main parts. The 1st part shortly summarizes the history of life science research in space from the late 40s until today with focus on Europe and Germany, followed by a part on describing flight opportunities including the Space Shuttle/Spacelab system and the International Space Station ISS; in the 3rd part it focuses on extraordinary success stories of this constantly challenging research program and highlights some important key findings in space life science research. The book introduces in the 4th part innovative developments in non-invasive biomedical diagnostics and training methods for astronauts that emerge from this program and are of benefit for people on Earth especially in the aging society. Last but not least in its 5th part it closes with an outlook on the future of space life sciences in the upcoming era of space exploration. The book is intended for students and research scientists in the life sciences and biomedicine as well as for interested lay persons, who wish to get an overview of space life science research: its ́ early days, current status and future directions.
Cell Electrophoresis
This book presents a summary of the application and instrumentation of cell electrophoresis. The method of making cell purification and characterization possible according to the cellular negative surface charge density is discussed, and ideas for future developments are explained. The negative electrostatic forces at cell surfaces provide information about cell-cell interaction, blood vessel sealing, cytokine actions, cell transformation, ion transport phenomena, and other biological phenomena. Recalculations of the physical principles of cell electrophoresis reveal possibilities for removing disruptive factors caused by electrical current, heat, and sedimentation. The introduction of computer technology, the performance of simultaneous two-parameter measurements, and the application of cell-friendly but current-inert buffer systems render the method more reliable and efficient.
Cardiovascular System, Red Blood Cells, and Oxygen Transport in Microgravity
This book comprehensively describes the physiological changes and consequences that occur in humans during spaceflight. It specifically presents the adaptations of the cardiovascular and the respiratory system. Specific changes occurring after 10, 20 or more days in space are depicted. Furthermore, the book explains various effective countermeasures that are required upon return of the astronauts to Earth. The book is a must-have for all biomedical and clinical researchers in the field of cardiovascular biology and respiration, and a fascinating reading for all interested laymen, who wish to understand a bit more about spaceflight research and technology.
Radiation in Space: Relevance and Risk for Human Missions
This volume of the series Springer Briefs in Space Life Sciences explains the physics and biology of radiation in space, defines various forms of cosmic radiation and their dosimetry, and presents a range of exposure scenarios. It also discusses the effects of radiation on human health and describes the molecular mechanisms of heavy charged particles’ deleterious effects in the body. Lastly, it discusses countermeasures and addresses the vital question: Are we ready for launch? Written for researchers in the space life sciences and space biomedicine, and for master’s students in biology, physics, and medicine, the book will also benefit all non-experts endeavouring to understand and enter space.
Vestibulo-Oculomotor Research in Space
This monograph describes the findings of spaceflight research related to spatial orientation, sensorimotor coordination and mental function. Exposed to the microgravity conditions of spaceflight, the human experiences a variety of physiological and psychological problems, which are presented here. Recent findings of sensory motor research in space are depicted and their benefits for life on earth discussed. The examination of the vestibulo-oculomotor system for example has led to the development of innovative devices for the measurement of three-dimensional eye and head movements. These devices are currently employed in Earthbound applications such as eye laser surgery. The book is written for students and researchers in neurosciences, biomedical engineering, for neurologists and psychologists as well as for persons wanting to know more about biomedical research in space and its application on earth.
Exercise in Space
This volume of the Series SpringerBriefs in Space Life Sciences summarizes the newest finding in the field of mental health and physiological exercise in Space. Currently two major challenges are impacting human health in the western societies, one being a move towards a sedentary society, the second one being longevity. Both have a considerable impact on physical as well as mental health. Space life science research helps to understand the underlying degenerative physiological and neuro-psychological processes as living in space, living in microgravity can be regarded as a time lapse of the sedentary and aging human being. Translational research of the past years has shown that exercise can be regarded as a key factor to counteract physical and mental deconditioning in space, guaranteeing a holistic approach to health and a benefit to the socio-demographic changes of our society. The book is written for scientists in biomedicine, more specific in aging research, sports physiology and neurosciences.
Gravitational Biology II
This volume of the series Space Life Sciences provides insights into the latest findings of gravity research and the effect of gravity on biological systems, specifically on a cellular and molecular level. It starts by explaining the underlying physics of gravity and presenting some novel ideas on the basic principles of gravity perception. It then goes on to discuss how, in response to gravity perception, secondary messengers such as calcium and hydrogen peroxide, might control responses further downstream, like gene and protein expression and modulation. Further, it describes the consequences for animal and plant cells as well as for metabolism. Written by experts in the field, this book is a valuable resource for students and researchers in biochemistry, medicine and biomedicine, wanting to gain a solid understanding of membrane biology, secondary messenger function and gene and protein expression, specifically in the context of gravity.
The NeuroMuscular System: From Earth to Space Life Science
The book provides fundamental new insights in the structure and function of the healthy NeuroMuscular system. Recent findings suggest that the musculoskeletal system that supports movement control on Earth is controlled by unique principles of structural, biochemical and molecular characteristics. Mechanical loading by working against normal gravity helps to support principal structures in bone, muscle and associated subcellular scaffold components. Disuse or immobilization of the body in bed rest on Earth or in microgravity in Space result in considerable loss of bone, muscle and force with downregulation of neuromuscular activity resulting in impaired performance control. The goal is to develop exercise prescriptions to maintain postural control in normal life, aging and rehabilitation on Earth as well as for an adequate human performance management in Space.
Nutrition Physiology and Metabolism in Spaceflight and Analog Studies
This book provides an overview of microgravity-induced changes in human metabolism, muscle, bone and the cardio-vascular system, and discusses in detail the nutrient uptake required during spaceflight to counteract these adaptive mechanisms and ensure an improved physical constitution upon returning to Earth. It addresses the needs of professors, researchers and students working in the field of human physiology and nutrition.
Advances in Photosynthesis Research
The Sixth International Congress on Photosynthesis took place from 1 to 6 August 1983, on the Campus of the "Vrije Universiteit Brussel", in Brussels, Belgium. These Proceedings contain most of the scientific contributions offered during the Congress. The Brussels Congress was the largest thus far held in the series of International Congresses on Photosynthesis. It counted over 1100 active participants. The organizers tried to minimize the disadvantages of such a large size by making maximum use of the facili ties available on a university campus. Most contributions were offered in the form of posters which were displayed in a substantial number of classrooms. The discussion sessions, twice ...
