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This volume contains most of the invited lectures presented at the second "Interna tional Symposium on the Evaluation of Cardiac Dynamics by Ultrasound" which was held on May 27-28, 1982, in Hamburg. Main topics of the symposium dealt with new echocardiographic technologies such as the transesophageal technique and digital image processing of echocardio grams, as well as with latest clinical and experimental results in the fields of contrast and Doppler echocardiography, tissue characterization and analysis of left ventricular function. We are greatly indebted to all participants who kept a very tight schedule in order to have these proceedings available at the time of the meeting. We cordia...
In recent years considerable progress and new developments in diagnostic and interventional cardiology have been observed, such as balloon angioplasty of coronary artery stenoses, reperfusion techniques in acute myocardial infarction, new pacing, and cardioversion-defibrillation techniques in ventricular tachyar rhythmias. On 5-8 May, 1985, an international symposium on 'Invasive Cardio vascular Therapy' was held in Cologne, which provided a survey on the experi ment~l and routine therapeutic measures presently available and practiced in cardiovascular medicine. This volume is based on the oral presentations given during the symposium. In five chapters the most important traditional and new ...
This volume contains the proceedings of the Fourth International Symposium on Coronary Heart Disease, held in Frankfurt/Federal Republic of Germany. In 1970, when the fIrst symposium was held, the whole range of diagnostic and therapeutic measures was covered, but since then interest in coronary heart disease has increased so considerably that the fourth symposium was restricted to only two therapeutic aspects, angioplasty and intracoronary thrombolysis. It can be noted with pleasure that European cardiologists, namely Andreas Griintzig and Peter Rentrop, have made essential contributions to the applicability of these modes of treatment. When angioplasty was fIrst discussed at the Third Inte...
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The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications. This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock. The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death. This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.
The first edition of this book was quite successful. As in the first edition, the book is divided into two major sections: cardiac muscle and coronary circula Several complimentary book reviews appeared soon tion. The book is multidisciplinary and includes after the first edition was published, and written and membrane biophysics, electrophysiology, physiol oral words of praise and appreciation were given both ogy, pathophysiology, pharmacology, biochemistry, to the publisher and to me by quite a few individuals. and ultrastructure. Thus, the book attempts ro It is because of such positive comments and reactions that the publisher and I decided to embark on a integrate all relevant aspects o...
The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion.
Sect. 1. Why women's health? -- Sect. 2. The role of women in health care and research -- Sect. 3. Reproductive health -- Sect. 4. Sexually transmitted diseases -- Sect. 5. International women's health -- Sect. 6. Women at work -- Sect. 7. Social determinants of health -- Sect. 8. Environmental exposures -- Sect. 9. Autoimmune disorders -- Sect. 10. Cardiovascular disease and cardiovascular risk in women -- Sect. 11. Cancer -- Sect. 12. Mental Disorders -- Sect. 13. Poorly understood conditions -- Sect. 14. AgingContributors. -- Preface. -- Women, Health, and Medicine: -- Why Women's Health? -- An Overview of Women and Health, M.B. Goldman & M.C. Hatch. -- Gender, Race and Class: From Epidemiologic Association to Etiologic Hypotheses, C.J. Rowland Hogue. -- The Role of Women in Health Care and Research: -- Section Editor: S.G. Haynes. -- Role of Advocacy Groups in Research on Women's Health, B. Seaman & S.F. Wood. -- State-of-the-Art Methods for Women's Health Research, S.G. Haynes & M ...
When I gave a presentation on return to work after heart valve replacement at the Tenth Congress of the German Society for Thoracic and Cardiovascular Surgery in 1981, I was surprised by the relatively low level of interest that cardiac surgeons seemed to have in this subject. This stimulated me to intensify my research in this area and to extend it to patients with coron ary heart disease. Obviously, physiological and mechanical aspects of medical treatment are of special interest to the surgeon. For the majority of cardiac surgical patients, that is those with coronary heart disease, the technical problems of the operative procedure have been solved to a great extent. Many studies have demonstrated that, aside from reduction of symptoms, aortocoronary bypass operation can lead to improvement of cardiac performance un der stress conditions. However in spite of the technical solutions to hemodynamic problems, it has become very clear that the reintegration of patients into their social sphere has not been accomplished to the extent that might be expected, as exempli fied by the relatively low rate of postoperative return to work.