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Chemical Modelling covers a wide range of disciplines and is the first stop for any materials scientist, biochemist, chemist or molecular physicist wishing to acquaint themselves with major developments and current opinion in the applications and theory of chemical modelling.
Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introduct...
Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. - Discusses the current state of electrostatics in biomolecular simulations and future directions - Includes information on time and length scales in lipid bilayer simulations - Includes a chapter on the nature of lipid rafts
Annual Reports in Computational Chemistry is a new periodical providing timely and critical reviews of important topics in computational chemistry as applied to all chemical disciplines. Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Each volume is organized into (thematic) sections with contributions written by experts. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists. Annual Reports in Computational Chemistry is a "must" for researchers and students wishing to stay up-to-date on current developments in computational chemistry.* Broad coverage of computational chemistry and up-to-date information * Topics covered include bioinformatics, drug discovery, protein NMR, simulation methodologies, and applications in academic and industrial settings * Each chapter reviews the most recent literature on a specific topic of interest to computational chemists
For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ—mainly the two families of claudins and TAMPs—several other functions have been discovered, a striking one being the surprising finding that some claudins form paracellular channels for small ions and/or water. This Special Issue includes 43 articles covering numerous dedicated topics including pathogens affecting the TJ barrier, TJ regulation via immune cells, the TJ as a therapeutic target, TJ and cell polarity, function and regulation by proteins of the tricellular TJ, TJ as a regulator of cellular processes, organ- and tissue-specific functions, TJ as sensors and reacting to environmental conditions, and last but not least, TJ proteins and cancer.
Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
As improvements in living conditions and advances in modern medicine lead to increased life expectancy and the number of older adults world-wide continues to grow, so the number of older individuals with cardiac and cerebrovascular disease is rising. Over eighty per cent of all cardiovascular disease-related deaths now occur in patients aged sixty five or older. The high prevalence of co-morbidities, frailty and cognitive decline amongst older patients requires that a holistic approach to the management of cardiovascular disease is required. Written and edited by leading experts in the field, ‘Cardiovascular diseases and health in the older patient’ provides scholarly evidence and data w...
How does the brain work? After a century of research, we still lack a coherent view of how neurons process signals and control our activities. But as the field of computational neuroscience continues to evolve, we find that it provides a theoretical foundation and a set of technological approaches that can significantly enhance our understanding.
The field of cardiac arrhythmias has been evolving so fast during the last years that scientific meetings are frequently necessary to present technological advances, to communicate results of relevant and innovative researches, to assess the impact of recently developed diagnostic and therapeutical tools, to discuss controversial aspects, and to reach a consensus on the most appropriate evaluation and management of specific problems. This is the main reason why in 1988 we started to organize a biannual International Workshop on Cardiac Arrhythmias. Since then many editions of the workshop have taken place and over the years the fame and popularity of the event have increased continuously. This book contains the Proceedings of the Eighth Edition of the Workshop th th held in Venice at the Fondazione Giorgio Cini from the 5 to the 8 of October 2003. During the meeting all the principal aspects of the different arrhythmias, from epidemiology to physiopathology, electrogenetic mechanisms, diagnosis, prognosis, treatment, pshycological implications and economic costs have been discussed among the numerous experts and participants.
This new edition of the comprehensive and renowned textbook Principles and Practice of Geriatric Medicine offers a fully revised and updated review of geriatric medicine. It covers the full spectrum of the subject, features 41 new chapters, and provides up-to-date, evidence-based, and practical information about the varied medical problems of ageing citizens. The three editors, from UK, USA and France, have ensured that updated chapters provide a global perspective of geriatric medicine, as well as reflect the changes in treatment options and medical conditions which have emerged since publication of the 4th edition in 2006. The book includes expanded sections on acute stroke, dementia, card...