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Immunobiology of Bone Marrow Transplantation
Bone marrow transplantation, the goal which integrates hemato logists, immunologists, geneticists, oncologists and specialists of several other fields, has overcome its state of stagnation in recent years. Clinically as well as experimentally new approaches to old problems and new conclusions from recent findings proliferate: bone marrow transplantation in leukemic remission, bone marrow growth in cell culture, bone marrow manipulation with antisera, bone marrow differentiation in histoincompatible hosts, immuno suppression with partial body irradiation to cite just a few. These and other new developments were discussed by experts from 12 countries in and outside the European Community during an international seminar held on March 8-10, 1979 by the "Institut fur Hamatologie, GSF", under the auspices of the European Communities. The editors thank both the contributors to this symposium, who made it a successful meeting and submitted their manuscripts punctually, and the publishers, who have provided a volume of high quality in good time. They are also grateful for the valuable cooperation from numerous colleagues at the Institut fur Hamato logie.
Immunological Diagnosis of Leukemias and Lymphomas
This two-and-a-half-day symposium has concentrated on main aspects of the rapidly expanding field ofleukocyte markers in hematology. While leukemias are already being 'phenotyped' routinely in clinical centers, continued research on the developmental sta ge of cells and cell membranes, expanding into a malignant clone, permits new snap shots on hemopoietic differentiation. Thus the discovery of leukemia-associated anti gens, which so far have not been found on subpopulations of normal cells, has greatly stimulated the discussion on 'differentiation antigens versus tumor antigens'. The proceedings reflect the considerable success which has been achieved very re cently in the classification of...
Modern Trends in Human Leukemia III
"Es ist ja ganz eineriei, wer es gejunden hat, die Hauptsache ist, daB es gejunden worden ist." This was said by Hermann Wilbrand, director of the department of opthalmology at the university hospital Hamburg-Eppendorf (1919-1923), when others claimed priority for the long searched for cortical visuell center, which he had discovered. Five years ago we tried in Wilsede an unusual experiment, bringing together for three long days and nights scientists and medical doctors to learn like students about each others work. The hope was that the participants in the workshop would discuss the whole problem of human leukemia, and coopera tive programmes among the different specialized research groups ...
Protides of the Biological Fluids
Protides of the Biological Fluids: Proceedings of the 25th Colloquium, Brugge, 1977 focuses on the structure, metabolism, transformations, and reactions of protides of biological fluids. The selection first takes a look at the structure and metabolism of plasma lipoproteins, including phosphatidylinositol exchange protein from bovine brain; structural integrity of the mitochondrial adenine nucleotide carrier; and reassembly of the monosaccharide transport system of the human erythrocyte in black lipid membranes. The book then discusses species and dietary effects on lipoprotein apoprotein metabolism in vivo; transfer of surface and core lipids of a lipoprotein from plasma into aortic wall; a...
Biological Regulation and Development
The motivation for us to conceive this work on regulation was mainly our belief that it would be fun, and at the same time productive, to approach the subject in a way that differs from that of other treatises. We thought it might be interesting and instructive-for both author and reader-to examine a particular area of investigation in a framework of many different problems. Cutting across the traditional boundaries that have separated the sub jects in past volumes on regulation is not an easy thing to do-not because it is difficult to think of what interesting topics should replace the old ones, but because it is difficult to find authors who are willing to write about areas outside those p...
Advances in Cancer Research
Advances in Cancer Research
The Microcirculation.
The presently accepted model of the circulation is based on the work of Dr. William Harvey in the 17th century. But what Dr. Harvey described was what we now call the Macrocirculation, this is, the heart, lungs, arteries, and veins. The technology at the time did not permit a study of the capillaries, the interstitial fluid, and the lymphatic system. How did oxygen and other molecules traveled from the capillary lumen to the parenchymal cells was not known. A lot of scientific knowledge has been acquired since Dr. Harvey's description. Dr. Marcello Malpighi, and Italian physician and biologist, visualized and discovered the capillaries also in the 17th Century. Claude Bernard, a French physi...
Vascular Complications in Human Disease
Recently, there have been several major advances in our understanding of the causes of diseases affecting the heart, lungs, kidneys, skin and blood vessels. This book offers a concise and carefully composed collection of reviews on vascular biology. Each chapter is written by an internationally respected authority in the field and is a state of the art review of important parts of basic and clinical science.
