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Anna-Lucia Carapia and her friend, Kara, were regular girls with naturally inquisitive natures. Natures that, one winter's day, would lead them to a deviant cult and drag them down into the dangerous underworld they had created.
This volume constitutes the thoroughly refereed post-conference proceedings of the 10th International Workshop on Agent-Oriented Software Engineering, AOSE 2009, held in Budapest, Hungary, in May 2009 as part of AAMAS 2009, the 8th International Conference on Autonomous Agents and Multiagent Systems. The 10 revised full papers presented were carefully selected from numerous initial submissions during two rounds of reviewing and improvement. The papers have been organized into three sections on multi-agent organizations, concrete development techniques, and - one step higher - going beyond the concrete technique and proposing a development method for designing concrete types of systems. This state-of-the-art survey is rounded off by five additional lectures addressing key areas in development: agent-oriented modelling languages, implementation of MAS, testing of MAS, software processes, and formal methods for the development of MAS. They permit analysis of the current state in the generation of specifications of MAS, the way these specifications can be implemented, how they can be validated, and what steps are necessary to do so.
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
Even at the beginning of the new millenium the rare earths still remain, to a certain extent, a mystery. The chapters in this volume will help to unravel some of these. In the filling of the 4f electronic orbitals the lanthanides defy the elementary aufbau principle that underlies the periodic sequence of the elements, and the authors of the first chapter introduce the readers to the basic physics of the orbital collapse leading to that failure. Furthermore an explanation is offered in terms of double-well potentials. The phenomenon is illustrated using the valence transitions observed in some of the rare earth atoms, including Sm group metals and the higher oxides of cerium, praseodymium an...
The present volume of the Handbook of the History of Logic brings together two of the most important developments in 20th century non-classical logic. These are many-valuedness and non-monotonicity. On the one approach, in deference to vagueness, temporal or quantum indeterminacy or reference-failure, sentences that are classically non-bivalent are allowed as inputs and outputs to consequence relations. Many-valued, dialetheic, fuzzy and quantum logics are, among other things, principled attempts to regulate the flow-through of sentences that are neither true nor false. On the second, or non-monotonic, approach, constraints are placed on inputs (and sometimes on outputs) of a classical conse...
This book constitutes the refereed post-proceedings of the First International Workshop on Cognitive Agents for Virtual Environments, CAVE 2012, held at AAMAS 2012, in Valencia, Spain, in June 2012. The 10 full papers presented were thoroughly reviewed and selected from 14 submissions. In addition one invited high quality contribution has been included. The papers are organized in the following topical sections: coupling agents and game engines; using games with agents for education; visualization and simulation; and evaluating games with agents.
Nitric Oxide in Health and Disease: Therapeutic Applications in Cancer and Inflammatory Disorders presents updated information on the chemistry, signaling of newly derived therapeutic nitric oxide donors/inhibitors, and their complexes in liposomes or nanospheres in both pre-clinical and clinical activities. The book discusses many examples of research related to the application of novel therapeutic compounds that focus on a chemical—nitric oxide—and its applications that have been shown to exert significant therapeutic activities against various resistant cancers unresponsive to current treatments and different inflammatory diseases which continue to require novel treatments. This is a ...
Cancer is the leading cause of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females. In this book, we discussed various aspects of breast cancer carcinogenesis from clinics to its hormone-based as well as genetic-based etiologies for this deadly cancer. We hope that this book will contribute to the development of novel diagnostic as well as therapeutic approaches.