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Postgenomics
Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
Life Out of Sequence
Thirty years ago, the most likely place to find a biologist was standing at a laboratory bench, peering down a microscope, surrounded by flasks of chemicals and petri dishes full of bacteria. Today, you are just as likely to find him or her in a room that looks more like an office, poring over lines of code on computer screens. The use of computers in biology has radically transformed who biologists are, what they do, and how they understand life. In Life Out of Sequence, Hallam Stevens looks inside this new landscape of digital scientific work. Stevens chronicles the emergence of bioinformatics—the mode of working across and between biology, computing, mathematics, and statistics—from t...
Welcome to the Genome
The popular introduction to the genomic revolution for non-scientists—the revised and updated new edition Welcome to the Genome is an accessible, up-to-date introduction to genomics—the interdisciplinary field of biology focused on the structure, function, evolution, mapping, and editing of an organism's complete set of DNA. Written for non-experts, this user-friendly book explains how genomes are sequenced and explores the discoveries and challenges of this revolutionary technology. Genomics is a mixture of many fields, including not only biology, engineering, computer science, and mathematics, but also social sciences and humanities. This unique guide addresses both the science of geno...
How We Became Our Data
We are now acutely aware, as if all of the sudden, that data matters enormously to how we live. How did information come to be so integral to what we can do? How did we become people who effortlessly present our lives in social media profiles and who are meticulously recorded in state surveillance dossiers and online marketing databases? What is the story behind data coming to matter so much to who we are? In How We Became Our Data, Colin Koopman excavates early moments of our rapidly accelerating data-tracking technologies and their consequences for how we think of and express our selfhood today. Koopman explores the emergence of mass-scale record keeping systems like birth certificates and...
Intangible Intangibles
This book takes as its starting point recent debates over the dematerialisation of subject matter which have arisen because of changes in information technology, molecular biology, and related fields that produced a subject matter with no obvious material form or trace. Arguing against the idea that dematerialisation is a uniquely twenty-first century problem, this book looks at three situations where US patent law has already dealt with a dematerialised subject matter: nineteenth century chemical inventions, computer-related inventions in the 1970s, and biological subject matter across the twentieth century. In looking at what we can learn from these historical accounts about how the law responded to a dematerialised subject matter and the role that science and technology played in that process, this book provides a history of patentable subject matter in the United States. This title is available as Open Access on Cambridge Core.
Algorithmic Modernity
"The rhetoric of algorithmic neutrality is more alive than ever-why? This volume explores key moments in the historical emergence of algorithmic practices and in the constitution of their credibility and authority since 1500. If algorithms are historical objects and their associated meanings and values are situated and contingent-and if we are to push back against rhetorical claims of otherwise-then the genealogical investigation this book offers is essential to understand the power of the algorithm. The fact that algorithms create the conditions for many of our encounters with social reality contrasts starkly with their relative invisibility. More than other artifacts, algorithms are easily...
Mattering
Feminists today are re-imagining nature, biology, and matter in feminist thought and critically addressing new developments in biology, physics, neuroscience, epigenetics and other scientific disciplines. Mattering, edited by noted feminist scholar Victoria Pitts-Taylor, presents contemporary feminist perspectives on the materialist or ‘naturalizing’ turn in feminist theory, and also represents the newest wave of feminist engagement with science. The volume addresses the relationship between human corporeality and subjectivity, questions and redefines the boundaries of human/non-human and nature/culture, elaborates on the entanglements of matter, knowledge, and practice, and addresses bi...
Scouting and Scoring
An in-depth look at the intersection of judgment and statistics in baseball Scouting and scoring are considered fundamentally different ways of ascertaining value in baseball. Scouting seems to rely on experience and intuition, scoring on performance metrics and statistics. In Scouting and Scoring, Christopher Phillips rejects these simplistic divisions. He shows how both scouts and scorers rely on numbers, bureaucracy, trust, and human labor to make sound judgments about the value of baseball players. Tracing baseball’s story from the nineteenth century to today, Phillips explains that the sport was one of the earliest fields to introduce numerical analysis, and new methods of data collection were supposed to enable teams to replace scouting with scoring. But that’s not how things turned out. From the invention of official scorers and Statcast to the creation of the Major League Scouting Bureau, Scouting and Scoring reveals the inextricable connections between human expertise and data science, and offers an entirely fresh understanding of baseball.
A Final Story
Towards a Final Story is the first history of the modern scientific epic. These epic stories pull together our knowledge of the universe, uniting material and biological origins, from beginning to end. The authors of these epics--among them Carl Sagan, E.O. Wilson, and Steven Weinberg--saw their task as providing an integrated schema that would not only bring together but also go beyond the particular scientific results and disciplines available as they wrote their histories. Nasser Zakariya traces how such epic stories could achieve what they claimed, how they inhabit culture and politics, and how they arrived at the present moment from a period in the previous century when inquiries into ultimate origins were regarded by many as unscientific and unanswerable. These prominent, popular historical narratives of science are important forms of knowledge in their own right. They expose what science means in the wider culture and at the same time focus attention on the near paradoxical nature of a universal history narrated by humanity for humanity.
The Maternal Imprint
Introduction: The Maternal Imprint -- Sex Equality in Heredity -- Prenatal Culture -- Germ Plasm Hygiene -- Maternal Effects -- Race, Birth Weight, and the Biosocial Body -- Fetal Programming -- It's the Mother! -- Epilogue: Gender and Heredity in the Postgenomic Moment.
