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A Concise Guide to Statistics
  • Language: en
  • Pages: 118

A Concise Guide to Statistics

The text gives a concise introduction into fundamental concepts in statistics. Chapter 1: Short exposition of probability theory, using generic examples. Chapter 2: Estimation in theory and practice, using biologically motivated examples. Maximum-likelihood estimation in covered, including Fisher information and power computations. Methods for calculating confidence intervals and robust alternatives to standard estimators are given. Chapter 3: Hypothesis testing with emphasis on concepts, particularly type-I , type-II errors, and interpreting test results. Several examples are provided. T-tests are used throughout, followed important other tests and robust/nonparametric alternatives. Multiple testing is discussed in more depth, and combination of independent tests is explained. Chapter 4: Linear regression, with computations solely based on R. Multiple group comparisons with ANOVA are covered together with linear contrasts, again using R for computations.

Statistical Design and Analysis of Biological Experiments
  • Language: en
  • Pages: 281

Statistical Design and Analysis of Biological Experiments

This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed ...

Advances in Systems Biology
  • Language: en
  • Pages: 679

Advances in Systems Biology

The International Society for Systems Biology (ISSB) is a society aimed at advancing world-wide systems biology research by providing a forum for scientific discussions and various academic services. The ISSB helps coordinate researchers to form alliances for meeting the unique needs of multidisciplinary and international systems biology research. The annual International Conference on Systems Biology (ICSB) serves as the main meeting for the society and is one of the largest academic and commercial gatherings under the broad heading of ‘Systems Biology’.

Combinatorial Pattern Matching
  • Language: en
  • Pages: 453

Combinatorial Pattern Matching

  • Type: Book
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  • Published: 2005-05-13
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  • Publisher: Springer

This book constitutes the refereed proceedings of the 16th Annual Symposium on Combinatorial Pattern Matching, CPM 2005, held in Jeju island, Korea on June 19-22, 2005. The 37 revised full papers presented were carefully reviewed and selected from 129 submissions. They constitute original research contributions in combinatorial pattern matching and its applications. Among the application fields addressed are computational biology, bioinformatics, genomics, proteinomics, data compression, Sequence Analysis and Graphs, information retrieval, data analysis, and pattern recognition.

Positive Systems
  • Language: en
  • Pages: 385

Positive Systems

  • Type: Book
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  • Published: 2009-09-30
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  • Publisher: Springer

This volume contains the proceedings of the "Third Multidisciplinary Symposium on Positive Systems: Theory and Applications (POSTA09)" held in Valencia, Spain, September 2–4, 2009. This is the only world congress whose main topic is focused on this field.

Research in Computational Molecular Biology
  • Language: en
  • Pages: 495

Research in Computational Molecular Biology

This book constitutes the refereed proceedings of the 12th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2008. It presents current issues in algorithmic, theoretical, and experimental bioinformatics.

Algorithms in Bioinformatics
  • Language: en
  • Pages: 388

Algorithms in Bioinformatics

  • Type: Book
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  • Published: 2011-08-31
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  • Publisher: Springer

This book constitutes the refereed proceedings of the 11th International Workshop on Algorithms in Bioinformatics, WABI 2011, held in Saarbrücken, Germany, in September 2011. The 30 papers presented were carefully reviewed and selected from 77 submissions. They cover aspects of algorithms in bioinformatics, computational biology and systems biology.

Computational Life Sciences II
  • Language: en
  • Pages: 279

Computational Life Sciences II

  • Type: Book
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  • Published: 2006-11-23
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  • Publisher: Springer

This book constitutes the refereed proceedings of the Second International Symposium on Computational Life Sciences, CompLife 2006. The 25 revised full papers presented were carefully reviewed and selected from 56 initial submissions. The papers are organized in topical sections on genomics, data mining, molecular simulation, molecular informatics, systems biology, biological networks/metabolism, and computational neuroscience.

Algorithms in Bioinformatics
  • Language: en
  • Pages: 485

Algorithms in Bioinformatics

  • Type: Book
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  • Published: 2004-10-29
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  • Publisher: Springer

This book constitutes the refereed proceedings of the 4th International Workshop on Algorithms in Bioinformatics, WABI 2004, held in Bergen, Norway, in September 2004. The 39 revised full papers presented were carefully reviewed and selected from 117 submissions. Among the topics addressed are all current issues of algorithms in bioinformatics, such as exact and approximate algorithms for genomics, genetics, sequence analysis, gene and signal recognition, alignment, molecular evolution, phylogenetics, structure determination or prediction, gene expression and gene networks, proteomics, functional genomics, and drug design.

Research in Computational Molecular Biology
  • Language: en
  • Pages: 631

Research in Computational Molecular Biology

  • Type: Book
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  • Published: 2006-08-12
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  • Publisher: Springer

This volume contains the papers presented at the 10th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2006), which was held in Venice, Italy, on April 2–5, 2006