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The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.
The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.
TWO MONTHS AFTER their disastrous holiday, Orlagh and Jerry are at home in Ireland recovering from their terrifying ordeal. The Belgae Torc is at last on display at the National Museum and Orlagh is under increasing pressure to divide her time between her work at the museum and heading up an archaeological dig in County Meath. She is convinced that an ancient battle between Iron Age tribes took place here and is determined to prove her theory, but as archaeologists begin to unearth the truth, they are faced with some unexpected surprises. Meanwhile, on the other side of the Atlantic, Jack Harrington is making discoveries of his own and finds himself juggling personal and professional commitm...
Our worldview determines our perception of reality and thus shapes our attitude to life and the way we live. If our worldview adequately reflects reality, we can lead an authentic and meaningful life that we will later look back on with satisfaction. A mature worldview is much more than the accumulation of facts and experiences. Whereas in the past there was primarily a lack of scientific insight, today it is above all the immense flood of information and opinions that obscures our view of essential knowledge. It is therefore not surprising that people's views sometimes differ considerably with regard to fundamental questions of life. The thesis of this book is that in this age it is possibl...