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Advances in RNA-sequencing (RNA-seq) technologies have provided an unprecedented opportunity to explore the gene expression landscape across individuals, tissues, and environments by efficiently profiling the RNA sequences present in the samples. When a reference genome sequence or a transcriptome of the sample is available, mapping-based RNA-seq analysis protocols align the RNA-seq reads to the reference sequences, identify novel transcripts, and quantify the abundance of expressed transcripts.The reads that fail to map to the human reference, known as unmapped reads, are a large and often overlooked output of standard RNA-seq analyses. Even in carefully executed experiments, the unmapped r...
This book constitutes the proceedings of the 16th International Symposium on Bioinformatics Research and Applications, ISBRA 2020, held in Moscow, Russia, in December 2020. The 23 full papers and 18 short papers presented in this book were carefully reviewed and selected from 131 submissions. They were organized in topical sections named: genome analysis; systems biology; computational proteomics; machine and deep learning; and data analysis and methodology.
This book constitutes the proceedings of the 12th International Symposium on Bioinformatics Research and Applications, ISBRA 2016, held in Minsk, Belarus, in June 2016. The 25 papers presented in this volume were carefully reviewed and selected from 77 submissions. They were organized in topical sections named: next generation sequencing data analysis; protein-protein interactions and networks; protein and RNA structure; phylogenetics; sequence analysis; and statistical methods.
The book covers a range of topics dealing with emerging computing technologies which are being developed in response to challenges faced due to scaling CMOS technologies. It provides a sneak peek into the capabilities unleashed by these technologies across the complete system stack, with contributions by experts discussing device technology, circuit, architecture and design automation flows. Presenting a gradual progression of the individual sub-domains and the open research and adoption challenges, this book will be of interest to industry and academic researchers, technocrats and policymakers. Chapters "Innovative Memory Architectures Using Functionality Enhanced Devices" and "Intelligent Edge Biomedical Sensors in the Internet of Things (IoT) Era" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Offering a carefully reviewed selection of over 50 papers illustrating the breadth and depth of computer architecture, this text includes insightful introductions to guide readers through the primary sources.
Presents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers: General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seeding, and approximation algorithms Algorithms and tools for genome and sequence analysis, including formal and ...
Introduction to Gauge Field Theory provides comprehensive coverage of modern relativistic quantum field theory, emphasizing the details of actual calculations rather than the phenomenology of the applications. Forming a foundation in the subject, the book assumes knowledge of relativistic quantum mechanics, but not of quantum field theory. The book is ideal for graduate students, advanced undergraduates, and researchers in the field of particle physics.
Designed as a sequel to the authors' Introduction to Gauge Field Theory, Supersymmetric Gauge Field Theory and String Theory introduces first-year graduate students to supersymmetric theories, including supergravity and superstring theories. Starting with the necessary background in quantum field theory, the book covers the three key topics of high-energy physics. The emphasis is on practical calculations rather than abstract generalities or phenomenological results. Where possible, the authors show how to calculate, connecting the theoretical with the phenomenological. While the field continues to advance and grow, this book addresses the basic theory at the core and will likely remain relevant even if more advanced ideas change.
This book analyzes the social forces and political coalitions driving regional integration projects in Asia with a focus on ASEAN and Indonesian conglomerates. It asks which social forces, within the domestic political economy of Asian states, are driving governments to seek regional arrangements for economic governance. In particular the book asks how the emergence, reorganization, and expansion of capitalist class have conditioned political support for regional economic integration. By addressing these issues, the book emphasizes that the wellspring of regional economic institution projects stem from the process of capitalist development and the social forces it has unleashed. The book’s...
Based on the modern approach of information theory, this book presents novel experimental techniques, tools, and data processing methods for physics applications. It shows readers how to plan and conduct experiments, design and certify measuring equipment, and process and interpret the experimental data. Drawing on his extensive experience in experimental research, the author discusses the theory of systems for measuring and recording data, the equipment and methods used for studying fast processes, the basic methods of experimental physics, and the methods for interpretation and data processing. Bringing together approaches that have previously been scattered in the literature, the book covers high-speed photography, Fourier optics, spectroscopy, interferometry, holography, electromagnetic waves, X-rays, and corpuscular investigation.