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Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.
Skin is our primary interface with the environment, and T cells are crucial for orchestrating host immune responses against pathogenic microorganisms. Dysregulated immune responses, on the other hand, can result in chronic inflammatory skin diseases. The complex regulatory networks include effector T cells, memory T cells, regulatory T cells, immunoregulatory co-signaling molecules and cytokines that control skin immunity, and the mechanisms that regulate skin immune responses in host defense and in immune-mediated cutaneous diseases. The immune-regulatory networks are involved in the common inflammatory skin diseases, including psoriasis, atopic dermatitis, alopecia areata, vitiligo, bullous diseases, and cutaneous adverse drug reaction. The goal of this Research Topic is to provide a forum to advance research on the contribution of skin inflammation to the genesis and development of the skin diseases as well as to explore innovative skin-oriented pharmacological interventions, mainly on the immune regulatory networks, in the attempt to achieve a beneficial impact on the skin disease course.
Handbook of Skin Disease Management Learn the essential information necessary to manage patients with skin diseases in this brand-new compact handbook Skin diseases severely impact quality of life and management of these conditions can be exceptionally challenging, particularly when first and second-line treatments have failed. The Handbook of Skin Disease Management is the first handbook specifically developed with the focus on the management aspect of dermatological conditions. It is designed to be used by busy clinicians who need relevant information quickly and includes an A-Z format with succinct entries loaded with essential information. Incorporating evidence bases and success rates f...
Die 9. Auflage von Rook's Textbook of Dermatology steht für: - die Nummer 1 im Bereich der Dermatologie mit allem Wissenswerten zu dem Fachgebiet - ein unverzichtbares Referenzwerk für alle Dermatologen. - ein herausragendes Nachschlagewerk, das als Printausgabe und E-Book erhältlich ist und alle Krankheitsbilder in der Dermatologie umfassend abdeckt. - eine vollständig überarbeitete Auflage, in der jede Erkrankung in einem einheitlichen Format präsentiert wird. - einen neuen Ansatz bei der Klassifizierung von Erkrankungen: Die Zahl der Kapitel wurde verdoppelt (jetzt 160 statt vormals 80 Kapitel). Alle Kapitel sind nach logischen Abschnitten organisiert, mit einem komplett neuen Inhal...
2017 PROSE Award Winner - Multivolume Reference/Science The world's number 1 dermatology information resource Universally respected, Rook's Textbook of Dermatology is the most comprehensive, definitive and best-illustrated reference work for dermatologists of all levels worldwide and has been at the forefront of international dermatology publishing since first appearing in 1968. The Ninth Edition has been radically re-engineered to match the modern day challenges faced by dermatologists. Once again it has been published as a combined digital and print resource, but with a new online platform enabling easier and faster navigation. A common structure to describe and discuss each disorder has b...
Since the first cases of an acute respiratory illness were reported, the pathogen SARS-coV-2 (severe acute respiratory syndrome coronavirus 2) and its disease, COVID-19 have disrupted the world and changed the course of medical history. Clinics were under lockdown and supplies of critical drugs such as biologics and meladinine were delayed. The prolonged impact of disease has taken its toll on patients, their careers, medical staff, research and medical education. Shortly after the first landmark studies of COVID-19 vaccine trial data were made known, global mass vaccination programs were underway. Vaccine technology has expanded beyond messenger RNA (mRNA) to include non-replicating viral v...
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