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Annual Reports in Medicinal Chemistry
Over the last ten years, it has become increasingly obvious that sudden death represents the major challenge confronting cardiology in the last part of the XXth Century. Careful epidemiologic studies have established the magnitude of this overall important problem of public health. The frequent association of sudden death with coronary artery disease has been demonstrated. Some of the electrophysiologic mechanisms underlying lethal arrhythmias have been unveiled. In addition, clinical markers permitting identifica tion of high risk individuals have emerged. Finally, different studies have raised some hope as to the ability of therapeutic interventions to protect these patients against a prem...
New edition of the classic complete reference book for cardiologists and trainee cardiologists on the theory and practice of electrocardiography, one of the key modalities used for evaluating cardiology patients and deciding on appropriate management strategies.
Sudden death is probably the greatest challenge facing modem cardiology today. This is mainly due to the impact of its brusque appearance and the socioeconomic implications. The incidende is presently decreasing somewhat, mainly due to the decline in new cases of ischemic heart disease on one hand, and to better preven tion in risk patients on the other. Nevertheless, the figures are still high and represent over 300.000 patients per year in the United States alone. This book is an updating of the problem of sudden death from a multifactorial standpoint. It includes not only electrophysiologic data but also covers aspects ranging from epidemiology to prevention. Risk markers and triggering m...
First multi-year cumulation covers six years: 1965-70.
Reflex Control of the Circulation presents an interdisciplinary discussion of concepts in the reflex control of circulation. This volume describes aspects of autonomic receptor physiology, central pathways of reflex control, the electrophysiology of cardiovascular afferents, the interaction between reflexes, the autonomic control of regional blood flows, the autonomic control of fluid and electrolyte balance, and neurohumoral control of the circulation through normal and pathological states (e.g., hypertension, congestive heart failure). In addition, the regulation of regional blood flow during exercise and developmental aspects of reflex control are examined. Any researcher interested in the autonomic system and its role in circulation will find this book fascinating reading.
correction of such a reentry when he observed The W olff-Parkinson-White (WPW) syndrome, . . . in a favourable experiment, the vigorous the most common variety of preexcitation, has for some time held a fascination for those circulating wave and its instantaneous arrest by interested in clinical electrophysiology because section of the ring is a sight not easily forgotten. it seems to represent a naturally occurring event which, if adequately understood, would un Courageous is the only way to describe the mask answers to many fundamental questions first attempt to surgically interrupt an accessory concerning mechanisms and treatment of car pathway. The immensity of the feat speaks for diac a...
In the last 15 years we have had the opportunity to teach Electrocardiography to many different types of student: doctors preparing to become cardiologists, cardiologists attending weekly 'refresher' sessions at our hospital, general practitioners who wish to become adept at electrocardiography and attend our yearly courses and, finally, the medical students of the Universidad Aut6noma of Barcelona. We cover everything with these students from the basics of electrophysiology to applied electrocardiographic semiology. This quadruple experience has proved stimulating, constantly motivating the search for better and more precise material, and the most appropriate didactic presentation for each type of student, each of whom has different requirements. I have always felt that didactic capability is not related to the intelligence of the professor, or to the amount of knowledge this person possesses, but really depends on the 'quality' of this knowledge, the 'desire' to transmit it and the 'capacity' to adapt to each teaching situation.
The saying, "What one does not know, one does not recognize", applies to the interpretation of the electrocardiogram. Recently a wealth of new information on the electrocardiogram has become avail able by correlating electrocardiographic findings with information from new techniques such as His bundle recordings, programmed stimulation of the heart, 24-hour record ing~, and cardiac scintigraphy. Also, our knowledge about the electrocardiogram has been extended by acquiring new epidemiologic data and by follow-up studies on patients with myocardial infarction and bundle branch block. Unfortunately, this new information has to be dug out of several different journals and books. This book bring...