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Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
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This book focuses on the representation of dermatological diseases in pigmented skin, fills an important gap in the literature, and facilitates better dermatological diagnosis when dealing with patients of various ethnicities. It discusses over 400 diseases and their representations with the help of over 2000 high-quality images and illustrations. This book elaborates on each single disease using easy-to-follow schematics and a focused approach to facilitate reader learning. Pursuing a comprehensive, the book covers not only common skin diseases such as psoriasis, lichen planus, eczema, erythrasma, cutaneous tuberculosis, leprosy, leishmaniasis and oral submucous fibrosis, but also rare trop...
Gets traders and investors up to speed on the hottest new approach to predicting the markets One of the most talked-about new forecasting tools in today's international markets, dynamic technical analysis (DTA) arms traders and investors with unprecedented insights into market volatility, price changes, and market trends. DTA is also a valuable money management tool and is much easier for money managers to master than traditional technical analysis techniques. The first practical introduction to this powerful new approach, Dynamic Technical Analysis provides readers with all the tools and know-how necessary to unlock the full power of DTA. * The only guide devoted exclusively to a powerful new forecasting technique * Uses numerous real-world trading examples to quickly acquaint readers with state-of-the art DTA principles and practices Phillippe Cahen (Paris, France) is Head of Technical Analysis for Credit Lyonnais Capital Markets in Paris.
What is the appropriate way to taste wine at a restaurant? What type of wine is best served with catfish? 1000 Best Wine Secrets contains all the information novice wine drinkers and experienced connoisseurs alike need to feel comfortable in any restaurant, home or vineyard. 1000 Best Wine Secrets is the book for readers seeking the confidence to select and enjoy the perfect bottle from among the wines of the world. Includes such tips as: Secrets of buying great wine Detecting faulty wine and sending it back Serving wine like a pro Wine tips from around the globe—from Argentina to France and Spain to California Knowing when to drink wine
Should Anne risk arrest and scandal to help a fugitive escape? Her decision will change her life. In 1628, with England torn by conflict, fifteen-year old Anne Dudley helps a rebel escape from Tattershall Castle through the watery fens. Pursued by the sheriff and his men, who view her Puritan family as traitors to the king, Anne risks more than the loss of her reputation as the daughter of the earl's steward - she also risks death. Set in a period when women and men were burned or hanged for their religion, the novel tells the story of a girl who must cope with a woman’s feelings while she struggles with romantic turmoil, political danger, and doubts about her own beliefs. When she takes up her pen, we glimpse the grown Anne Dudley Bradstreet, whose Colonial writings are still loved and honored today. From a talented new voice in historical fiction, Gretchen Gibbs’ Anne of the Fens joins The Book of Maggie Bradstreet in The Bradstreet Chronicles. Records about the author's well-known ancestors give birth to her stories. Read the series—enriched by the historical content in each book's back pages—in any order.
This volume provides recent advances in the field of biophysics of membrane proteins. Chapters are divided into several parts: detailing biochemistry and functional analysis, experimental and theoretical structural determinations, membrane protein dynamics, and conformation studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Biophysics of Membrane Proteins: Methods and Protocols aims to provide comprehensive protocols with notes to help further the understanding of key membrane protein structure and function for students, academics, and industrial researchers.
Henrik Johan Ibsen was a major 19th-century Norwegian playwright, theatre director, and poet. He is often referred to as "the father of realism" and is one of the founders of Modernism in theatre. Ibsen's later work examined the realities that lay behind many facades, revealing much that was disquieting to many contemporaries. It utilized a critical eye and free inquiry into the conditions of life and issues of morality. The poetic and cinematic early play Peer Gynt, however, has strong surreal elements. Ibsen is often ranked as one of the truly great playwrights in the European tradition. Richard Hornby describes him as "a profound poetic dramatist-the best since Shakespeare". He is widely regarded as the most important playwright since Shakespeare. He influenced other playwrights and novelists such as George Bernard Shaw, Oscar Wilde, Arthur Miller, James Joyce, Eugene O'Neill and Miroslav Krleza. Ibsen was nominated for the Nobel Prize in Literature in 1902, 1903 and 1904.
Although a number of edited collections deal with either the languages of the world or the languages of particular regions or genetic families, only a few cover sign languages or even include a substantial amount of information on them. This handbook provides information on some 38 sign languages, including basic facts about each of the languages, structural aspects, history and culture of the Deaf communities, and history of research. This information will be of interest not just to general audiences, including those who are deaf, but also to linguists and students of linguistics. By providing information on sign languages in a manner accessible to a less specialist audience, this volume fills an important gap in the literature.
This book explores the larger realm of the knowledge infrastructure where texts are received, reconstructed, and sent over global networks.The sixteen essays collected in The Digital Word continue Landow and Delany's exploration of the new fluid, digitized text begun in Hypermedia and Literary Studies (1991), which focused on the linking of text, graphics, or sound into structures typically bound within a single computer or local-area network. This book explores the larger realm of the knowledge infrastructure where texts are received, reconstructed, and sent over global networks. It covers text management, textual resources and communication, and working with texts.In their introductory ess...