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Structure and Function in Excitable Cells
This book is a collection of up-to-date research reviews dealing with various aspects of the structure and function of excitable cells. Its overall objective is to further the search for a better understanding of the mechanism of excitation on a structural and physicochemical basis. The chapters are written by active investigators from a variety of disciplines, repre senting many different points of view. Their complementary fields of expertise give this book the rare feature of extraordinary breadth. Excitability is a fundamental property of many biological systems. The mechanisms by which nerve impulses are initiated and propagated, and by which rhythmical activities are produced in nerve, muscle, and cardiac cells, can be fully elucidated only when the process of excitation is derived from fundamental principles applied to known structural forms, at both the macroscopic and the molecular level. The problems of excitation are complex, requiring knowledge of many aspects of cells, including their morphology, elec trobiology, chemical physics, and biochemistry.
Voltage-Sensitive Ion Channels
Voltage-sensitive ion channels are macromolecules embedded in the membranes of nerve and muscle fibers of animals. Despite decades of intensive research under the traditional approach of gated structural pores, the relation between the structure of these molecules and their function remains enigmatic. This book examines physically oriented approaches not covered in other ion-channel books, and it develops a new physics-based approach to the problem of molecular excitability.
International Review of Cytology
International Review of Cytology
Pathways of a Cell Biologist
This book is the autobiography of Shinya Inoué, tracing his life from childhood to the present. Though he has made many contributions to science, perhaps the most remarkable one involves the visualization of dynamics in living cells by means of a polarizing light microscope, an innovation that changed the face of cell biology. Addressing readers curious to know why and how he achieved such success, the story begins with a prologue describing the end of World War II and Inoué’s lifelong collaborator, the great cell biologist Katsuma Dan. Following the prologue, the author’s childhood and teenage experiences during World War II are described, before the focus shifts to his scientific career and personal life. The book not only offers important tips for young researchers, it will also help them develop a passion for science.
Cell Reproduction
Cell Reproduction: In Honor of Daniel Mazia represents the proceeding of a symposium entitled "Cell Reproduction held in Keystone, Colorado, on March 1978. The symposium is organized to honor Daniel Mazia. Most of the areas of research that are discussed at the conference have their origins in Dan Mazia's laboratory. This volume is divided into nine parts, consisting of papers presented in the symposium. It first focuses on the macromolecular control in cell proliferation and growth, cell cycle regulation, control of genetic expression, and microtubule assembly in vitro and in vivo. In then explains the control of fertilization phenomena, chromosome movement, the mitotic apparatus, and control of cell division and cell cleavage. Lastly, this volume discusses the structural and molecular basis of cell movement and describes the differentiated cell. This book represents a tribute to Daniel Mazia's extraordinary contributions as teacher, scientist, and friend.
