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It has been 10 years since Plenum included a series of reviews on bacte riophages, in Comprehensive Virology. Chapters in that series contained physical-genetic maps but very little DNA sequence information. Now the complete DNA sequence is known for some phages, and the se quences for others will soon follow. During the past 10 years two phages have come into common use as reagents: A phage for cloning single copies of genes, and Ml3 for cloning and DNA sequencing by the dideoxy termi nation method. Also during that period the use of alternative sigma fac tors by RNA polymerase has become established for SPOl and T4. This seems to be a widely used mechanism in bacteria, since it has been im...
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
The pteridines in their multitude of forms fulfill many roles in nature ranging from pigments to cofactors for numerous redox and one-carbon transfer reactions. This extraordinary diversity of function is unified by the unique chemistry of the pteridine heterocycle. The International Symposium on the Chemistry and Biology of Pteridines and Folates is a forum for presenting recent and exciting advances in this expanding field. In of ideas results that has often stimulated bringing together various disciplines, a synergy fresh approaches to major problems. The Tenth International Symposium held at Orange Beach, Alabama, March 21-23, 1993, proved no exception by providing new insights into fola...
Proceedings of the Fourth International Workshop on ANCA and the Second International Colloquium on Wegener's Granulomatosis and Vasculitic Disorders held in Lubeck, Germany, May 28-30, 1992
This volume records the papers presented in Chieti, Italy, at the 1991 meeting of the International Society for Arterial Chemoreception (ISAC). This was the eleventh of a series of assemblies held since 1959. This field of research, which examines the critical function and mechanisms of O and pHIPC0 sensitive cells in 2 2 the body, is unique in that it encompasses diverse biological and medical areas. The reader of this book will note chapters concerning modem techniques like in situ hybridization; analysis of cell membrane channels and intracellular ion movements; immunohistochemistry of peptides, hormones, and the corresponding receptors of chemoreceptor cells; and systemic analysis of ref...
This is the first book-length study of the history of gerontology. It shows how old age became a 'problem' worth investigating and how a mulitidisciplinary orientation took shape.
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A COMPREHENSIVE RESOURCE ON GERONTOLOGY AND GERIATRICS Since its inception in 1987, The Encyclopedia of Aging has proven to be the definitive resource for scholars and students across the burgeoning and increasingly interdisciplinary fields of gerontology and geriatrics. Like its three esteemed predecessors, the fourth edition contains concise, readable explorations of hundreds of terms, concepts, and issues related to the lives of older adults, as well as timely coverage of the many new programs and services for the elderly. Updated, under the distinguished stewardship of editor-in-chief Richard Schulz to reflect the infusion of new information across the scientific disciplines, this new ed...