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Arterial Chemoreception
Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid. Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis. Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body. Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases. Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments. This book is a required text for any researcher in the field of arterial chemoreception for years to come. It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.
Chemoreception
Since 1959, the International Society of Arterial Chemoreception (ISAC) has organized in a variety of countries fifteen scientific meetings devoted to the mechanisms of peripheral arterial chemoreception and chemoreceptor reflexes. After the meeting held in Philadelphia with Sukhamay Lahiri as president, ISAC membership elected Lyon (CNRS, University Claude Bernard, France) as the site of the xv" ISAC Symposium. The Symposium was effectively held in Lyon from the 18th to the 22nd of November 2002 and Jean-Marc Pequignot was its president. The organizers were Jean-Marc Pequignot and Yvette Dalmaz Lyon (CNRS, University Claude Bernard, France) and the Scientific Committee was formed by John Ca...
Lung Development
Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
Biology of the Mammary Gland
Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of thes...
Elastin and Elastic Tissue
Although elastin was first identified and purifled in 1840, relatively few, major advances to determine its structure and function occurred between then and 1970. This was pointed out by Carl Franzblau in his recent review (1). This sad state of affairs does not detract, however, from the importance of contributions made during the last 50 years; many of these are referred to in the various chapters that comprise this monograph. I would be remiss not to emphasize the pioneering work of S. M. Partridge, who, in 1955, reported on a technique to obtain virtually pure elastin. It was, indeed, a privilege to have the participation of Dr. Partridge in the First International Conference on Elastin,...
Arterial Chemoreceptors
This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017). Each article contains original data and represents up-to-date information concerning the carotid body and oxygen sensing in health and disease. This volume is a required text for all researchers in the field of arterial chemoreception and will provide a valuable reference source for years to come.
The Carbonic Anhydrases
As we approach the twenty-first century the problems of industrialization are evident: we find there is a greenhouse effect, the ozone layer is being depleted, the rain is acidified, and there is a terrible problem of increasing C0 concentrations in the atmo 2 sphere. The carbonic anhydrases are a unique family of enzymes that solve these problems in the human body: they are responsible for converting C0 (a gas) to 2 HC0-, which is the biggest intracellular buffer, with a concomitant decrease in a 3 hydroxyl ion. Globally, the functions of the carbonic anhydrases in photosynthesis in rain forests and in the algae and plankton that cover our oceans indicate that they are also of utmost import...
Angiogenesis
Proceedings of the 5th Biannual International Meeting on Angiogenesis: From the Molecular to Integrative Pharmacology, held July 1-7, 1999, in Crete, Greece. Angiogenesis, as a vastly complex biological process, has challenged researchers from all basic scientific disciplines, including pharmacology, biochemistry, physiology, embryology and anatomy. The significance of this phenomenon for the study of disease states has also interested clinicians from a number of specialist fields. This multidisciplinary work reflects the growth of awareness of concepts such as angiogenesis based therapy, the enormous therapeutic and commercial potential of which has attracted major research and investment in recent years. This volume, which aims to bridge the gap between basic and clinical methodology and understanding, presents the most up-to-date developments in this field.
Selected Topics in Environmental Biology
Selected Topics in Environmental Biology covers the proceedings of the 26th International Congress of Physiological Sciences on Environmental Biology, held in New Delhi, India on October 20-26, 1974. The symposium is arranged in the subjects of high altitude and under water physiology and the physiological effects of cold, heat, and accelerations. This book is organized into 13 sections encompassing 74 chapters. The opening part deals with the principles and mechanisms of thermoregulation, with emphasis on the role of neurotransmitters in temperature regulation. The succeeding parts examine metabolic aspects and adaptive mechanisms to cold and heat stress. These parts also survey the thyroid...
Control of Respiration
The scientific literature has expanded dramatically in recent years, making entry into the structure of any given area extremely difficult; concurrent with this explosion more people are required to become acquainted with information outside their main line of expertise. For this reason there is a need for review articles which give an overall review of circumscribed areas. This volume reviews the subject of respiratory control mechanisms; the authors of each chapter are active research workers engaged in the area covered by their chapter. The first four chapters are concerned with the basic physiological mechanisms which sense changes in the respiratory system, in the standard physiology te...
