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Leading scientists from different countries around the world contributed valuable essays on the basic applications and safety, as well as the ethical and moral considerations, of the powerful genetic engineering tools now available for modifying the molecules, pathways, and phenotypes of species of agricultural, industrial and even medical importance. After three decades of perfecting such tools, we now see a refined technology, surprisingly unexpected applications, and matured guidelines to avoid unintentional damage to our and other species, as well as the environment, while trying to contribute to solve the biological, medical and technical challenges of society and industry. Chapters on ...
Examining the long-lasting effects of European colonization on Mexican populations The Biocultural Consequences of Contact in Mexico explores how Mexican populations have been shaped both culturally and biologically by the arrival of Spanish conquistadors and the years following the defeat of the Aztec empire in 1521. Contributors to this volume draw on a diverse set of methods from archaeology, bioarchaeology, genetics, and history to examine the response to European colonization, providing evidence for the resilience of the Mexican people in the face of tumultuous change. Essays focus on Central Mexico, Yucatan, and Oaxaca, providing a cross-regional perspective, and they highlight Mexican...
Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the use of chemoinformatics in drug design. To that end, experts in all areas of drug discovery have made their knowledge available through a series of articles that report state-of-the-art approaches. Readers are provided with outstanding contributions focusing on a wide variety of topics which will be of great value to those interested in the many different and exciting facets of drug design.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The IWA Conference on Environmental Biotechnology: Advancement in Water and Wastewater Application in the Tropics, held in Kuala Lumpur, Malaysia on 9-10 December 2003, was a peer-reviewed conference. It was specially organized for Malaysia and the Asia-Pacific region in collaboration between Universiti Teknologi Malaysia (UTM), the International Water Association (IWA), the Malaysia Water Association and the Malaysian Biotechnology Directorate. Papers presented in the conference covered current perspectives on the advancement of water and wastewater applications using environmental biotechnology, as well as methodologies, techniques, modelling, case studies, directions and other specific is...
This book explores the journey of biotechnology, searching for new avenues and noting the impressive accomplishments to date. It has harmonious blend of facts, applications and new ideas. Fast-paced biotechnologies are broadly applied and are being continuously explored in areas like the environmental, industrial, agricultural and medical sciences. The sequencing of the human genome has opened new therapeutic opportunities and enriched the field of medical biotechnology while analysis of biomolecules using proteomics and microarray technologies along with the simultaneous discovery and development of new modes of detection are paving the way for ever-faster and more reliable diagnostic methods. Life-saving bio-pharmaceuticals are being churned out at an amazing rate, and the unraveling of biological processes has facilitated drug designing and discovery processes. Advances in regenerative medical technologies (stem cell therapy, tissue engineering, and gene therapy) look extremely promising, transcending the limitations of all existing fields and opening new dimensions for characterizing and combating diseases.
The first two years of life represent a transition period when growth changes from predominantly growth hormone (GH) independent to GH dependent. This book, Growth Disorders and Acromegaly, includes two parts. The first part consists of five chapters that illustrate the nature, causes, types, signs, and symptoms of GH deficiency (GHD) and fetal growth restriction. It describes the impact of GH and its deficiency on different biological systems in children and adults. Also, this book assesses the role of human GH (hGH) and insulin-growth factor1 (IGF-1) gene families during pregnancy. This book offers several novel insights of GH in male reproductive health. The second part consists of three chapters that show the pegvisomant, colorectal neoplasms in acromegaly, epidemiology and underlying mechanisms, and the surgical managements of acromegaly. Finally, this book will be of interest to scientists, embryologists, neuroendocrinologists, neurotoxicologists, and physicians who follow recent developments in the field of growth disorders.