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Imaging Life
This volume provides an overview of a variety of approaches to biological image analysis, which allow for the study of living organisms at all levels of complexity and organization. These organisms range from individual macromolecules to subcellular and cellular volumes, tissues and microbial communities. Such a "systems biology" understanding of life requires the combination of a variety of imaging techniques, and with it an in-depth understanding of their respective strengths and limitations, as well as their intersection with other techniques. Howard, Brown, and Auer show us that the integration of these imaging techniques will allow us to overcome the reductionist approach to biology tha...
Quantitative Imaging in Cell Biology
This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric...
Nuclear Magnetic Resonance Imaging in Medicine and Biology
The aim of this book is to give a sound physical understanding of the theory and practice of NMR imaging, a field which has grown rapidly in recent years, to the point that clinical imaging systems have become commercially available worldwide and many techniques have evolved.
Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems
Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems, Volume 638, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sample chapters from this new release include In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe, Using FDAA probes to study cell division in Bacillus subtilis, Chemoenzymatic synthesis of UDP-sugars, Chemical tools for selective activity profiling of bacterial penicillin-binding proteins, Chemical Probes Reveal and Extraseptal Mode of Cross-linking in Staphylococcus Aureus, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Includes the latest information on retinoid signaling pathways
Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods
Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods, Volume 641 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include caged cyclopropanes with improved tetrazine ligation kinetics, an analysis of metabolically labeled inositol phosphate messengers by NMR, cell-permeant caged inositol pyrophosphates for probing ß-cells, imaging phospholipase D activity with clickable alcohols via transphosphatidylation, fluorescent biorthogonal labeling of class B GPCRs in live cells, near-infrared photoactivatable nitric oxide donors with integrated photoacoustic monitoring, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Includes the latest information on retinoid signaling pathways
Bio-Imaging
Highlights the Emergence of Image Processing in Food and AgricultureIn addition to uses specifically related to health and other industries, biological imaging is now being used for a variety of applications in food and agriculture. Bio-Imaging: Principles, Techniques, and Applications fully details and outlines the processes of bio-imaging applica
Advanced Imaging in Biology and Medicine
A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed sole...
Principles of Medical Imaging
Since the early 1960's, the field of medical imaging has experienced explosive growth due to the development of three new imaging modalities-radionuclide imaging, ultrasound, and magnetic resonance imaging. Along with X-ray, they are among the most important clinical diagnostic tools in medicine today. Additionally, the digital revolution has played a major role in this growth, with advances in computer and digital technology and in electronics making fast data acquisition and mass data storage possible. This text provides an introduction to the physics and instrumentation of the four most often used medical imaging techniques. Each chapter includes a discussion of recent technological developments and the biological effects of the imaging modality. End-of-chapter problem sets, lists of relevant references, and suggested further reading are presented for each technique. X-ray imaging, including CT and digital radiography Radionuclide imaging, including SPECT and PET Ultrasound imaging Magnetic resonance imaging
Advanced Imaging in Biology and Medicine
A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed sole...
Light Detectors, Photoreceptors, and Imaging Systems in Nature
The influence of light on the lives of living organisms is all-pervasive, affecting movement, vision, behavior, and physiological activity. This book is a biophysically grounded comparative survey of how animals detect light and perceive their surroundings. Included are discussions of photoreceptors, light emitters, and eyes. The book focuses in particular on the kinds of optical systems that have evolved, beginning with unicellular organisms that detect and respond to light through to more advanced and complex designs for imaging. The relevance of these studies extends beyond biology, since these findings can be used to help develop photoreceptor energy conversion and information systems, and optical imaging devices with a wide range of everyday applications. The book will appeal to biophysicists, photobiologists, bioengineers, neuroscientists, and all researchers working in the area of vision and visual optics.
