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In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the "epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. Thi...
This book offers a comprehensive update on mechanisms of tumorigenesis. The first portion discusses pediatric cancer, the influence of environmental factors and oncogene activity in tumorigenesis; the second portion is structured by organ site for easy access.
Ein Handbuch für die Praxis der Dispersionstechnologie: Weitverstreute Daten aus der Literatur, technische Details und ausgewählte theoretische Grundlagen wurden zu einer übersichtlichen, gut verständlichen Darstellung aufbereitet, die nicht mit Mathematik und komplizierten Zusammenhängen überfrachtet ist. An zahlreichen Beispielen wird erklärt, wie sich verschiedene Dispersionszustände in den Eigenschaften des Produkts widerspiegeln; die Wirkung eines Dispersionsmittels wird auf stoffliche Aspekte, nicht Handelsnamen zurückgeführt. Der Anwender wird in die Lage versetzt, 'seine' Dispersionen gezielt zu verändern, um mechanischen, chemischen und ökologischen Anforderungen der Kunden gerecht zu werden. Mit Herstellerlisten für die technische Ausrüstung! Geschrieben in erster Linie für die industrielle Praxis - weniger für akademische Forschung und Lehre.
This book provides a concise yet comprehensive resource on Diabetic Kidney Disease. Similar to the previous edition, the book reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are also covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease, 2e is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.
For nearly 60 years, Heptinstall’s Pathology of the Kidney has been the reference of choice for both pathologists and nephrologists for expert, authoritative coverage of kidney disease. The fully revised and reorganized Eighth Edition, edited by Drs. J. Charles Jennette, Vivette D. D’Agati, Agnes B. Fogo, Volker Nickeleit and Michael Barry Stokes offers thorough pathologic descriptions, important clinical correlations, and up-to-date discussions of causes and pathogenesis to improve understanding of kidney disease and to facilitate accurate diagnosis and optimum care of patients with kidney disease. Now in a single volume, this image-rich text conveys the unique challenges and intricacies of renal disease, offering powerful diagnostic and treatment recommendations from decades of clinical research.