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G Protein Pathways
This third volume in the trio covering G proteins, features integrated approaches to studying G proteins. Methods pertaining to signaling mechanisms are presented, including theoretical and modeling approaches, biochemistry and molecular biology, and cell biology and physiology. The techniques for studying the structure and function of G proteins are important not only to those with specific research interests in them, but also endocrinologists and pharmacologists conducting research on signaling mechanisms that are increasingly understood to interact with G proteins.
Suicide Risk Assessment and Prevention
This book explores suicide prevention perspectives from around the world, considering both professionals’ points of view as well as first-person accounts from suicidal individuals. Scholars around the globe have puzzled over what makes a person suicidal and what is in the minds of those individuals who die by suicide. Most often the focus is not on the motives for suicide, nor on the phenomenology of this act, but on what is found from small cohorts of suicidal individuals. This book offers a tentative synthesis of a complex phenomenon, and sheds some light on models of suicide that are less frequently encountered in the literature. Written by international experts, it makes a valuable contribution to the field of suicidology that appeals to a wide readership, from mental health professionals to researchers in suicidology and students.
Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood an...
Lipid Metabolism in Signaling Systems
Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume. - Techniques for examining the role of phosphoinositides in signal transduction - Techniques related to protein kinase C - Analysis of inositol phosphates - Techniques to analyze phospholipid turnover in the brain
Annual Report
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Live life: an implementation guide for suicide prevention in countries
This product addresses the global public health problem of close to 800 000 suicides every year, of which 79% occur in low- and middle-income countries. Suicide is the second leading cause of death in the age group 15-29 years. WHO guidelines already exist in the area of suicide prevention (https://www.who.int/mental_health/mhgap/evidence/suicide/en/); therefore, this product is not a guideline, but will ensure the implementation of the existing guidelines.
International Review of Cell and Molecular Biology
International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2008: 4.935. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists
