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John C. Walker -- George F. Sprague -- Sir Kenneth Blaxter -- Jay L. Lush -- Karl Maramorosch -- John O. Almquist -- Henry A. Lardy -- Glenn Wade Salisbury -- Wendell L. Roelofs -- Cornelis T. De Wit -- Don Kirkham -- Robert H. Burris -- Sir Ralph Riley, F.R.S. -- Ernest R. Sears -- Theodor O. Diener -- Ernest John Christopher Polge -- Charles Thibault -- Peter M. Biggs -- Michael Elliott -- Jozef Stefaan Schell -- Shang Fa Yang -- John E. Casida -- Perry L. Adkisson -- Carl B. Huffaker -- Morris Schnitzer -- Frank J. Stevenson -- Neal L. First -- Ilan Chet -- Baldur Rosmund Stefansson -- Gurdev S. Khush -- Roger N. Beachy -- James E. Womack -- Fuller W. Bazer -- R. Michael Roberts -- Steven D. Tanksley -- Longping Yuan -- Michel A.J. Georges -- Ronald L. Phillips -- John Anthony Pickett, CBE, DSc, FRS -- James H. Tumlinson -- W. Joe Lewis
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Curative anti-AIDS drug therapy still remains as an unconquered hurdle to drug research. This book covers significant aspects that are involved in the search, design and development of potential anti-AIDS agents with emphasis on areas related to drug development. These include enzyme inhibitors (reverse transcriptase, protease, glucosidase), inhibitors of gene expression (oligonucleotides), viral-binding inhibitors (anionic compounds and CD4 mimetics) and various plant derived products. A focus of this book is the medicinal chemistry of these classes of compounds. In addition, other areas that are pertinent to drug development are also addressed. These include HIV regulatory proteins, the development of anti-HIV-1 assays and resistance to anti-HIV-1 agents.