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Studies in Natural Products Chemistry
Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural produc...
Goat Medicine
Fully revised and expanded, Goat Medicine, Second Edition includes discussions on new diseases ranging from bovine spongiform encephalopathy to floppy kid disease as well as major updates on important diseases such as scrapie, mycoplasmosis, paratuberculosis, and urolithiasis. Information has also been added on management of transgenic goats and organic goat production. The text begins by outlining fundamentals of goat practice and moves on to systems-based coverage of the goat. Each chapter provides clinical anatomy and physiology of every system alongside information on relevant clinical signs, differential diagnosis, and system-specific disease.
Structure and Chemistry (Part E)
Structure and Chemistry (Part E)
The Chemistry of Natural Products
This book reviews in a concise and manageable way the progress in all key areas of natural products chemistry since 1984. The most significant advances are highlighted over a wide field of chemistry, structure, synthesis and biosynthesis. This book provides a unique and superb entry into the vast literature on the subject.
A Model of Human Occupation
Presenting the new edition of the text that delivers the most widely-used and developed conceptual model in occupational therapy. Beautifully redesigned and fully revised, the Third Edition of A Model of Human Occupation (MOHO) delivers the latest in human occupation research and application to practice. New to this edition: a reader-friendly format with second color and additional illustrations and anecdotes; more case examples for integrating the model into practice; a discussion of the therapy process and how change occurs; language linked to UT and ICIDH-2 terminology; a research chapter; and numerous research references highlighting the growing body of evidence supporting MOHO.
Jaagsiekte Sheep Retrovirus and Lung Cancer
Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.
Animal Allergens: Common Protein Characteristics Featuring their Allergenicity
Among the many molecules present in our environment, some have the property to induce allergic sensitization and IgE-mediated reactions. The analysis of known major animal allergens has shown that most belong to single protein families: lipocalins and serum albumins for inhalant allergens, EF-hand proteins, tropomyosins and caseins for the digestive allergens. The finding that allergens are often clustered in large families may be related to the fact that common structural, biochemical or functional features contribute to their allergenicity, in addition to external adjuvant factors. Currently, there is no curative treatment for animal allergy available. In order to lower allergic reactions to respiratory allergens in daily life and to food allergens upon accidental exposure, it is important to desensitize concerned patients. Tolerance induction by allergen-specific immunotherapy is in the current focus of an ambitious research. This Research Topic aims to provide a comprehensive view of the basic and recent insights on the allergenicity of animal allergens in view of their structural and functional aspects as well as allergen-specific immunotherapy.
Kielhofner's Model of Human Occupation
Updated throughout with the latest research, Kielhofner’s Model of Human Occupation, 6th Edition, is the definitive resource on the theory and application of the most widely used model in occupational therapy today. A client-centered approach explores what motivates each individual, how they select occupations and establish everyday routines, and how environment influences occupational behavior. This revised 6th Edition reflects the current framework and incorporates the most up-to-date MOHO theory, research, and application practices to give users complete preparation for today’s client care challenges.
