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This is the first book to make all the central concepts of discrete event simulation relevant for health technology assessment. Accessible to beginners, the book requires no prerequisites and describes the concepts with as little jargon as possible. It presents essential concepts, a fully worked out implementation example, approaches to analyze the simulations, the development of the required equations, model verification techniques, and validation. The book also covers various special topics and includes a real case study involving screening strategies for breast cancer surveillance.
The pharmaceutical industry is almost boundless in its ability to supply new drug therapies, but how does one decide which are the best medicines to use within restricted budgets? With particular emphasis on modeling, methodologies, data sources, and application to real-world dilemmas, Pharmacoeconomics: From Theory to Practice provides an introduc
A comprehensive compendium of the clinical trial data available, with each statin's different qualities explained, this text is intended as a guide to hypercholesterolaemia for both experienced clinicians and trainees.
The numbers of people with dementia continue to rise, and it remains one of the major medical and social challenges facing society. Unfortunately, dementia services are generally under-funded and are struggling to provide the comprehensive support needed by patients and their carers. This new book addresses the requirements needed to set up a modern dementia service and offers ideas on how to assemble them in a way that is tailored to local demand. It also outlines the development of the Dementia Action Team and is essential reading for all health professionals and managers involved in the care of patients with dementia.
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Cultural responses to most illnesses differ; dementia is no exception. These responses, together with a society's attitudes toward its elderly population, affect the frequency of dementia-related diagnoses and the nature of treatment. Bringing together essays by nineteen respected scholars, this unique volume approaches the subject from a variety of angles, exploring the historical, psychological, and philosophical implications of dementia. Based on solid ethnographic fieldwork, the essays employ a cross-cultural perspective and focus on questions of age, mind, voice, self, loss, temporality, memory, and affect. Taken together, the essays make four important and interrelated contributions to...
With the aim of improving the prevention, diagnosis and treatment of venous thromboembolism (VTE) in day-to-day clinical practices, this reference provides a wide range of perspectives from international specialists on research concerning this disorder, exploring subjects have an impact in the field, including VTE and pregnancy, hypercoagulable sta
The air pollution problem inevitably accompanies our human activities. Severe air pollution situations have been reported, especially in emerging countries, and satisfying the air quality standards fully remains an underlying issue. Today, modeling research is one of the more valuable approaches to understanding the behavior of air pollutants, and is useful for regulation-, policy- and decision-making. Such modeling applications range, with regard to horizontal grid resolution, from a few km (local) to hundreds of km (regional), to thousands of km (global). To foster our current scientific knowledge on modeling potentialities and limitations, scientific research related to multi-scale air pollution modeling is collected in this book.
The public health burden from lung cancer is substantial: it is the second most commonly diagnosed cancer and the leading cause of cancer-related deaths in the United States. Given the individual and population health burden of lung cancer, especially when it is diagnosed at later stages, there has been a push to develop and implement screening strategies for early detection. However, many factors need to be considered for broad implementation of lung cancer screening in clinical practice. Effective implementation will entail understanding the balance of potential benefits and harms of lung cancer screening, defining and reaching eligible populations, addressing health disparities, and many ...