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Heterocyclic Scaffolds I
Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams
Chirality and Biological Activity of Drugs
This book brings together the theoretical, commercial, and practical aspects of chirality and biological activity of drugs and acts as a ready reference for the effects of enantiomers of drug substances.
Main Group Metals in Organic Synthesis
This is the first handbook to cover in detail all aspects of this fascinating field of chemistry. In this handy two-volume set, readers will instantly find the information they need, clearly structured according to the individual metals in the main groups, hitherto only accessible after much time-consuming research. The result is in indispensable aid for everyday work in the lab. Alongside all the classical organic reactions, this book focuses on the modern variations as well as novel, current reactions in organic synthesis that are closely linked to main group elements - both stoechiometric and catalytic. With this work the two prizewinning editors have succeeded in producing a comprehensive compendium of the main group metals as reagents for organic reactions. In short, this is a must for every organic chemist, whether as an efficient introduction to current research, for retaining an overview or for looking up detailed information.
Progress in Medicinal Chemistry
The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research. The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT 3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey of the herb feverfew. The volume concludes, as it began, with enzyme inhibition - in this case concerning synthetic inhibitors of interstitial collagenases.
Handbook of Urology
Are you a urologist, trainee, or medical student managing patients with conditions like BPH, urinary stones or priapism? Do you require a rapid-reference guide to clinical management? If so, this full colour, practical handbook is the ideal resource, providing rapid-access information on the clinical management of all major urologic disorders and problems likely to be encountered daily. With a strong emphasis on user-friendliness and point-of-care accessibility, sections are divided according to the major areas of urology, with each chapter containing the following features: • case histories • multiple choice questions • key points box • key weblinks box • common errors in diagnosi...
Cardiovascular Function of Peripheral Dopamine Receptors
This volume deals with the consequences of activation of peripheral dopamine receptors impacting on the cardiovascular system, either the prejunctional neuroinhibitory dopamine receptor or the postjunctional dopamine receptor. It is useful for cardiovascular clinicians and receptor specialists.
