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Radioisotopes in the Human Body
Radioisotopes in the Human Body: Physical and Biological Aspects provides a unified presentation of the manner in which radioisotopes are deposited in the human body. This book focuses on bone structure and the irradiation of bone because so many of the available radioisotopes are deposited in bone. Organized into nine chapters, this book begins with an overview of the physical considerations that are significant to the dosimetry of internally deposited radioisotopes. This text then examines the structure and formation of bone in some detail. Other chapters consider the importance of bone in relation to potential radiation damage. This book discusses as well the relationship between radiation dose and radiobiological effects. The final chapter deals with the case of internal irradiation by radioisotopes. This book is a valuable resource for biologists, health physicists, scientists, and students. Radiation protection officers and individuals who have responsibilities for the safe use of radioactive substances will also find this book useful.
ADP-Ribosylating Toxins
ADP-ribosylating toxins have been the focus of intensive research for more than 30 years. Researchers from diverse fields of science have taken an interest in these bacterial toxins; they are studied, for example, by microbiologists, biochemists, cell biologists, and pharmacologists. There are two principal reasons for the broad and still growing interest in ADP ribosylating toxins. First, insights into the structure and functions of the toxins might be the key to prevention and treatment of diseases caused by the toxin-producing infectious micro organisms. Second, the ADP-ribosylating toxins provide potent and often unique pharmacological tools for the study of the physiological functions o...
Bacterial Protein Toxins
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
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Frontier Diplomats
This dual biography highlights the human dimensions of the Upper Missouri fur trade. Focusing on two major figures, Alexander Culbertson (1809-1879), trader with the American Fur Company, founder of Fort Benton, and the first white American to live among the Blackfeet Indians, and his wife, Natoyist-Siksina’ (“Holy Snake”) (1825-1893), daughter of Two Suns, the chief of the Blood (Kainah) tribe, Lesley Wischmann shows the great influence this couple had on the region. Culbertson and Natoyist-Siksina’ worked together for thirty years to promote cooperative relations between Native inhabitants and newly arrived white adventurers and played key roles in the Fort Laramie Treaty Conference of 1851 and treaty negotiations with the Blackfeet tribes in 1855. As she tells the story of these “frontier diplomats,” Wischmann also challenges conventional wisdom about the character of fur traders, the nature of the Blackfeet, and the role of Indian women.
