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This book describes the pathogenesis and treatment of several representative hematological disorders in children, with a special focus on genetic and molecular aspects. Research on the pathogenesis of hematological disorders in children has made remarkable strides; especially molecular target therapy has shown outstanding effects in refractory and conventional therapies for childhood leukemia. The findings presented in this book will broaden readers’ understanding and hopefully spark new discussions leading to the development of new therapies including cell therapy and molecular target therapy, allowing clinicians to use more effective and less toxic approaches in the future. Hematological Disorders in Children will appeal to a wide readership, from medical students and beginning investigators to experienced scholars in the field of pediatric hematology and oncology seeking to broaden their understanding and keep up with the latest developments. It will also be of interest to the parents of pediatric patients, and to co-medical staffs.
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Everyone has an opinion on transport: it significantly affects daily lives. This book highlights key transport opportunities and challenges, and identifies research requirements to inform policy discussion and support better societal outcomes. It does this by scanning across modes, continents, technologies and socio-economic settings, looking for common threads, points of difference and opportunities to make a difference. The book should appeal to prospective post-graduate students, professionals in transport and related fields, and those interested in better places and good discussions.
Autumn 1943. Realising his feelings for his sweetheart are not reciprocated, Major John Overton accepts a posting behind enemy lines in Nazi-occupied Albania. Arriving to find the situation in disarray, Overton attempts to overcome geographical challenges and political intrigues to set up a new camp in teh mountains overlooking the Adriatic. As he struggles to complete his mission amidst a chaotic backdrop, Overton is left to ruminate on loyalty, comradship and the futility of war.