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Molecular Design and Modeling
Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs.
Chemistry, 1981-1990
A collection of the Nobel Lectures delivered by the prizewinners in chemistry, together with their biographies, portraits and the presentation speeches.
The Lock-and-Key Principle
Published 100 years after Emil Fischer first proposed the lock-and-key principle, this volume provides a complete review of the subject to date and offers suggestions for futher research. The major impact of the lock-and-key principle on the chemical, biomedical and materials sciences is discussed by leaders in the field, with chapters dedicated to molecular recognition, nucleic acid and protein chemistry, crystallography and the development of Emil Fischer's initial ideas. The Lock-and-Key Principle is the most up-to-date review of progress in supramolecular chemistry and the lock-and-key principle and will become the essential guide to the past, present and future of this remarkable principle.
Anion Receptor Chemistry
Anion recognition plays a critical role in a range of biological processes, and a variety of receptors and carriers can be found throughout the natural world. Chemists working in the area of supramolecular chemistry have created a range of anion receptors, drawing inspiration from nature as well as their own inventive processes. This book traces the origins of anion recognition chemistry as a unique sub-field in supramolecular chemistry while illustrating the basic approaches currently being used to effect receptor design. The combination of biological overview and summary of current synthetic approaches provides a coverage that is both comprehensive and comprehensible. First, the authors de...
Lost Causes
What should be done with minors who kill, maim, defile, and destroy the lives of others? The state of Texas deals with some of its most serious and violent youthful offenders through “determinate sentencing,” a unique sentencing structure that blends parts of the juvenile and adult justice systems. Once adjudicated via determinate sentencing, offenders are first incarcerated in the Texas Youth Commission (TYC). As they approach age eighteen, they are either transferred to the Texas prison system to serve the remainder of their original determinate sentence or released from TYC into Texas’s communities. The first long-term study of determinate sentencing in Texas, Lost Causes examines t...
QSAR and Drug Design: New Developments and Applications
Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline.They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octanol/water) for compound series of medicinal-chemical interest are analysed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach.A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.
Biocomputing '98 - Proceedings Of The Pacific Symposium
The Pacific Symposium on Biocomputing brings together key researchers from the international biocomputing community. PSB is designed to be maximally responsive to the need for critical mass in subdisciplines within biocomputing. These proceedings contain peer-reviewed articles in computational biology.
Chemistry: 1981-1990
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Deadly Betrayal
The true story of an abducted and murdered child.
