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Neural Stem Cells
Many questions related to stem cell properties and neural stem cell lineage and differentiation still linger. This second edition revises and expands upon the successful first edition in order to provide the most current, cutting-edge methods of today for the scientists working to answer these questions. The use of these step-by-step, readily reproducible laboratory protocols will allow investigators to produce pure populations that can serve as a means of understanding the biology of neural stem cells and adapting them for transplantation into disease models. This is an excellent source of information and inspiration.
Neural Stem Cells
Over the last decade, neural stem cell research has provided penetrating insights into the plasticity and regenerative potential of the brain. Stem cells have been isolated from embryonic as well as adult central nervous system (CNS). Many non-CNS mammalian tissues also contain stem cells with a more limited repertoire: the replacement of tissue-specific cells throughout the li- time of the organism. Progress has been made in understanding fundamental stem cell properties that depend on the interplay of extrinsic signaling factors with intrinsic genetic programs within critical time frames. With this growing knowledge, scientists have been able to change a neural stem cell’s fate. - der ce...
Underlying Mechanisms of Epilepsy
This book is a very provocative and interesting addition to the literature on Epilepsy. It offers a lot of appealing and stimulating work to offer food of thought to the readers from different disciplines. Around 5% of the total world population have seizures but only 0.9% is diagnosed with epilepsy, so it is very important to understand the differences between seizures and epilepsy, and also to identify the factors responsible for its etiology so as to have more effective therapeutic regime. In this book we have twenty chapters ranging from causes and underlying mechanisms to the treatment and side effects of epilepsy. This book contains a variety of chapters which will stimulate the readers to think about the complex interplay of epigenetics and epilepsy.
Neurodegenerative Diseases
Proceedings of the Fifteenth Washington International Spring Symposium held at The George Washington University, Washington, D.C., May 15-17, 1995
Decolonial Puerto Rican Women's Writings
This book explores representations of sentient-flesh — flesh that holds consciousness of being — in Puerto Rican women’s literature. It considers how different literary devices can participate in the decolonization of the flesh as it is obfuscated by mappings of the 'body' from the Enlightenment era and colonial endeavors. Drawing on studies of cognitive development and epigenetics to identify how sentient-flesh creates knowledge of power and navigates methods of subversion for social justice, this book grapples with the question of how Puerto Rican women, living in the nation of their colonizer, manifest an identity that exists beyond the scope of colonization. It makes the case for a...
Genome Analysis
A complement to the bible of recombinant DNA, Molecular Cloning, these manuals are essential for every laboratory in which genes are being studied.
The Stem Cell Epistles
Human embryos, it has been said, "have no muscles, nerves, digestive system, feet, hands, face, or brain; they have nothing to distinguish them as a human being, and if one of them died, no one would mourn as they would for one of us." Consequently, early human embryos are being dismembered in laboratories around the world to produce embryonic stem cells, which, we are told, are the tools that will lead to the next quantum leap in medicine. Should Christians support such small sacrifices for something that might potentially relieve the suffering of millions, or should we vigorously oppose it? Developmental biologist and professor of biochemistry Michael Buratovich was asked such a question (...
The AGT Cytogenetics Laboratory Manual
Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic seque...
Neuroscience Data in the Cloud
The cloud model of data sharing has led to a vast increase in the quantity and complexity of data and expanded access to these data, which has attracted many more researchers, enabled multi-national neuroscience collaborations, and facilitated the development of many new tools. Yet, the cloud model has also produced new challenges related to data storage, organization, and protection. Merely switching the technical infrastructure from local repositories to cloud repositories is not enough to optimize data use. To explore the burgeoning use of cloud computing in neuroscience, the National Academies Forum on Neuroscience and Nervous System Disorders hosted a workshop on September 24, 2019. A broad range of stakeholders involved in cloud-based neuroscience initiatives and research explored the use of cloud technology to advance neuroscience research and shared approaches to address current barriers. This publication summarizes the presentation and discussion of the workshop.
