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Optimizing Outcomes and Addressing Adversities of Immunotherapy in Lung Cancer
  • Language: en
  • Pages: 179
Influence of potential diagnostic biomarkers in lung cancer
  • Language: en
  • Pages: 301

Influence of potential diagnostic biomarkers in lung cancer

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Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy
  • Language: en
  • Pages: 361

Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy

With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease. Thi...

AACR 2018 Proceedings: Abstracts 3028-5930
  • Language: en
  • Pages: 2995
Abeloff's Clinical Oncology E-Book
  • Language: en
  • Pages: 2648

Abeloff's Clinical Oncology E-Book

Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up. - Includes new chapters on Cancer Metabolism and Clinical Trial Designs in Oncology and a standalone chapter on lifestyles and cancer prevention. - Features extensive updates including t...

Advances in Systemic Therapy for Non-Small Cell Lung Cancer , An Issue of Thoracic Surgery Clinics
  • Language: en
  • Pages: 137

Advances in Systemic Therapy for Non-Small Cell Lung Cancer , An Issue of Thoracic Surgery Clinics

This issue of Thoracic Surgery Clinics, guest edited by Drs. Jyoti Patel and Jessica Donington, is devoted to Advances in Systemic Therapy for Non-Small Cell Lung Cancer. Drs. Patel and Donington have assembled expert authors to review the following topics: Adjuvant and Neoadjuvant Immunotherapy; Combining Immunotherapy with Radiation in Lung Cancer; Adjuvant Chemotherapy; ALK Mutations; Molecular Targets Beyond the Big 3; Advances in Systemic Therapy; Liquid Biopsies in NSCLC; Combining Immunotherapy and Chemotherapy for NSCLC; ROS-1 Mutations; EGFR Mutations; and more!

Lung Cancer and Personalized Medicine
  • Language: en
  • Pages: 236

Lung Cancer and Personalized Medicine

  • Type: Book
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  • Published: 2015-12-14
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  • Publisher: Springer

This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.

Key Trials in Cardiothoracic Surgery
  • Language: en
  • Pages: 152

Key Trials in Cardiothoracic Surgery

  • Type: Book
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  • Published: 2023-10-10
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  • Publisher: CRC Press

A concise summary of the most important clinical trials in cardiac and thoracic surgery. The focus is on how evidence-based decision making has helped to shape modern practice and guidelines. The key trials are described and an overview of their impact provided. Much research has been undertaken to study the efficacy of different drugs, techniques, and treatment strategies within cardiothoracic surgery. As a result, many randomised controlled trials have been published which discuss a wide variety of topics and with the intention of improving current practice and patient care. This volume presents a selection of the key trials and assesses their impact. Compact and easy to read, the distillation of core information will enable the reader to understand the importance of the key papers that have influenced best practice across operating theatres, clinics, multi-disciplinary meetings, and inpatient management. Including full summaries of more than 30 trials and reflecting the clinical scenarios encountered in everyday practice by cardiothoracic surgeons, this concise volume is written for both trainee and more experienced members of the surgical team.

The Bethesda Handbook of Clinical Oncology
  • Language: en
  • Pages: 1591

The Bethesda Handbook of Clinical Oncology

The Bethesda Handbook of Clinical Oncology is a clear, concise and comprehensive reference book for the busy clinician to use in his or her daily patient encounters. It focuses less on etiology, pathophysiology, and epidemiology, and considerably more on practical clinical information. Cancer management information is presented in a reader-friendly format that offers a comprehensive review of each disease along with the most commonly used treatment regimens, including chemotherapy dosing and schedules. Features: Clear, concise, complete reference book for busy clinician for daily patient management User-friendly formatting – tables, algorithms, charts, bullet points Contributors all from N...

Melanoma, An Issue of Hematology/Oncology Clinics
  • Language: en
  • Pages: 225

Melanoma, An Issue of Hematology/Oncology Clinics

This issue of Hematology/Oncology Clinics, guest edited by Dr. F. Stephen Hodi, is devoted to Melanoma. Articles in this issue include: The current state of Melanoma; Understanding the Biology of Melanoma Development and Therapeutic Implications; Surgical Management of Melanoma; Targeted Therapies for Cutaneous Melanoma; Treatments for Non-cutaneous Melanoma; Resistant Mechanisms and Therapeutic Implications; The Role of the Immune System in Melanoma Development and Treatment; Vaccines and Melanoma; IL-2, Interferon, and Cytokines; Immune Checkpoint Blockade; Adjuvant Treatments, Chance for Cure in Melanoma; and Combinatorial Approach to Treatment of Melanoma.