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Construction projects are usually completed through the efforts of several specialty contractors that enter into performance agreements with the prime contractor. Mistakes, whether made while bidding or when executing a construction project, can be costly for the facility owner, general contractor, or subcontractor. Focused on helping the project team avoid these mistakes and run their projects more efficiently, this book describes how a prime contractor can coordinate the efforts of subcontractors and address common problems that can occur during various stages. Greater understanding of problematic aspects can assure that the full scope of the project is covered without redundancy.
The young man is listening to Grandpa tell about the time he was a Deputy Sheriff. He sits on the edge of his seat as Grandpa tells about wild chases, murders he investigated, fights he had and the interesting calls he went on. Later in time, Grandpa passes away and the young man wishes he would have written down some of the things Grandpa said. Now those stories are gone forever. Michael Patrick retired in 2005 after a 33 year career in law enforcement. He realized he could be that "Grandpa" and unless he wrote his experiences down now they would be lost forever. "On The Beat" chronicles the law enforcement career of Michael Patrick. It tells about the agencies he worked for and the beats he worked. Read about wild car chases, a shooting he was in, murders he investigated, the fights and many of the interesting calls he went on. Read entries from a diary he kept in the beginning years when he was a "know-it-all rookie". "On The Beat" will give you an accurate picture of the career and personality of a veteran law enforcement officer....
This multidisciplinary book provides up-to-date coverage of carrier and spin dynamics and energy transfer and structural interaction among nanostructures. Coverage also includes current device applications such as quantum dot lasers and detectors, as well as future applications to quantum information processing. The book will serve as a reference for anyone working with or planning to work with quantum dots.
Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders.
According to the Sentencing Project, between 1980 and 2017, the number of incarcerated women increased by more than 750%, rising from a total of 26,378 in 1980 to 225,060 in 2017 and the number continues to rise. Dealing with incarcerated women and specifically psychopathic women can be challenging. Understanding Female Offenders: Psychopathy, Criminal Behavior, Assessment, and Treatment provides readers with a better conceptualization of the psychopathic/non-psychopathic female. This includes better ways of interviewing, assessing, and treating these women, and clinical caveats with case examples to assist with clinical applications. This is the only comprehensive resource that provides specific knowledge about female offenders, particularly on female psychopathy and assessment. - Describes the differences between ASPD and psychopathic women and men - Presents PCL-R, Rorschach, and PAI data on female offenders, female psychopaths, and female sex offenders - Reviews the current literature on female psychopathy studies - Provides in-depth female offender case studies - Discusses common biases in diagnosing, treating, and assessing in forensic settings with female offenders
An important new collection of clinical and preclinical reports on genetic therapy, this book describes illustrative examples of diseases in which gene-based interventions are presently plausible, and presents case studies of current research using both synthetic oligonucleotides and biological vectors. Combining the insights of over 50 contributors, Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors furnishes a historical overview of genetic therapy highlights official Food and Drug Administration positions on the preparation of oligonucleotides and vectors offers practical models of agent preparation, animal testing, pharmacokinetics, toxicology, and clinical trials disc...
The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general
In Great Minds In Management Ken G. Smith and Michael A. Hitt have brought together some of the most influential and original thinkers in management. Their contributions to this volume not only outline their landmark contributions to management theory, but also reflect on the process of theory development, presenting their own personal accounts of the gestation of these theories. The result is not only an ambitious and original panorama of the key ideas in management theory presented by their originators, but also a unique collection of reflections on the process of theory development, an area which to date little has been written about by those who have actually had experience of building t...