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Essence of Memory
This selection of reviews gives an up-to-date picture of memory research. Great progress has been made in identifying the memory trace at the molecular and cellular level and individual reviews address the major mechanisms by which changes in synaptic strength can persist. Exciting research at the systems level is also reviewed including the growing importance of changes in inhibitory interneurons and how they play a role in memory formation. Finally, reviews present cognitive and neurobiological models of human memory that explain, characterize and organize the act of memory within a coherent framework. - Provides an unique overview that covers all perspectives and methodological approaches to memory - Broad coverage of memory research from molecular to human studies in one source - Up-to-date reviews give the latest important ideas on memory formation
Nicolas-Louis De La Caille, Astronomer and Geodesist
This is the first comprehensive biography of one of the greatest and most careful observational astronomers of all time. He mapped the southern sky and named many of the constellations. In addition, he contributed to geodesy, navigation, and celestial mechanics.
Concepts at the Interface
This is an open access title available under the terms of a CC BY-NC-ND 4.0 International licence. It is free to read on the Oxford Academic platform and offered as a free PDF download from OUP and selected open access locations. Research on concepts has concentrated on how people apply concepts when presented with a stimulus. Equally important, however, is the use of concepts offline, while planning what to do or thinking about what is the case. There is strong evidence that inferences driven by conceptual thought draw heavily on special-purpose resources--sensory, motoric, affective, and evaluative. At the same time, concepts afford general-purpose recombination and support content-general...
North Pole 1983
Proceedings from a conference on the North Pole and region. 35 papers under the headings: geophysics, geography (3); oceanography, climatology (4); myths, history of circumpolar cartography (2), history of exploration (16th-20th centuries) (17); museums, films and philately dealing with the North Pole conquest (3); contemporary problems - maritime and air transportation, economic future and sea law (6).
The Price of Perfection
Few would question the necessity of artificial limbs for amputees. But what of surgery to lengthen the legs of children who are merely shorter than average? Hardly anyone would challenge the decision to prescribe Aricept to people with dementia. But is it acceptable to give the same medication to airline pilots seeking sharper mental focus on long-haul flights? Humans have engaged in biological self-improvement since long before recorded history, from the impotence-curing wild lotus brew of the ancient Egyptians to the herbal energy drink favored by early Olympians. Now biomedical enhancements are pushing the boundaries of possibility and acceptability. Where do we draw the line? How do we k...
The Violence of the Letter
The emergence of the alphabet in ancient Greece, usually heralded as the first step in the inexorable march toward reason and progress, in fact signaled the introduction of a chance technology that hijacked the future, with devastating consequences for humanity. By investigating an array of cultural artifacts, ranging from Kubrick's 2001: A Space Odyssey to the Oracle at Delphi to Luther's challenge to the Church, this book demonstrates how the apparently benign emergence of writing made possible far-ranging systems of organized domination and unprecedented levels of violence. The Violence of the Letter considers how a twenty-six-letter code changed the face of the world, and not always for the better.
Extrasynaptic neurotransmission as a way of modulating multiple neuronal functions
Extrasynaptic transmission is a unifying term for a wide variety of cellular processes, in which outside of synaptic terminals transmitter substances activate extrasynaptic receptors. Whereas “synaptic transmission” immediately refers to a process occurring at nerve terminals in which the arrival of a presynaptic impulse evokes exocytosis followed by a postsynaptic response within a millisecond time scale, extrasynaptic transmission has a wide diversity of ultrastructural and therefore mechanistic associated phenomena. In comparison to synaptic, extrasynaptic exocytosis may last for seconds or even minutes, thus expanding the timing of neuronal signaling. Extrasynaptic transmission has n...
