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Patch testing is the main tool of investigation in the diagnosis of allergic contact dermatitis. Its history is both fascinating and multifaceted. This book aims to acquaint readers with the current knowledge and the clinical features of allergic contact dermatitis and in the diagnosis of which is plays a great role.
This book is a compendium of tips on many different aspects of patch testing based on the recommendations of the International Contact Dermatitis Research Group (ICDRG), which is the reference group for all dermato-allergologists. It is intended to complement the book Patch Testing and Prick Testing: A Practical Guide by J.-M. Lachapelle and H. Maibach, which is an official publication of the ICDRG now in its third edition. Among the wide variety of topics covered are pitfalls, legal aspects, patch testing with ultrasonic bath extracts, the role of patch testing in occupational contact dermatitis and atopic dermatitis, semi-open tests, the implications of a negative test, patch testing validity, selection of extra allergens and patch testing in the tropics. Many illustrations are included and all information is completely up-to-date. This book will be of value to all practicing dermatologists.
Knowledge in the field of allergic contact dermatitis has grown to a great extent, due to recent advances in the chemical, immunological and clinical fields. These advances include the improved techniques of patch testing and prick testing, e.g. additional tests such as open, semi-open, repeated open application test (ROAT) and use tests, photopatch tests, atopy patch tests and provocative tests. Further, due to the ongoing changes in our environment, the series of patch tests – the so-called standards – are also regularly renewed. This new edition is completely revised, updated and expanded, with more colour illustrations. It is a universally useful and superb guide in the management of positive and negative patch test and prick test reactions, for all practicing dermatologists, from the beginner to the well-trained expert.
This third edition is an update on every conceivable aspect of the modern-day management of contact dermatitis. Both irritant and allergic contact dermatitis are covered clearly and comprehensively, special emphasis being given to occupational aspects as well as to prevention, diagnosis and treatment. The Textbook also covers epidemiology, the computerization of patch test data and patient information systems, noninvasive bioengineering measurement techniques, methods of skin testing other than patch testing, the histopathology of both irritant and all ergic contact dermatitis, and subjective reactions.
It is an unusual event for a textbook covering such a national and international networks and the use of highly specialized field as contact dermatitis to be standardized methodology, a highly differentiated published in its fourth edition within a time period picture can now be painted; we know the major p- of 13 years. When the European and Environmental fessions at risk, as well as the influences of age and Contact Dermatitis Research Group was founded in various cofactors. This is a solid basis for preventive 1985,one of the major goals was to edit a textbook of measures. A new allergen, described in one center, high scientific standard written by renown experts can now be tested on a la...
Hand eczema is a major complaint worldwide and a frequent occupational disorder. This book provides a comprehensive and detailed overview of the classification, etiology, diagnosis, prevention, and therapy of hand eczema. It is innovative, up to date, and practical. The links with particular occupations are explained, the various diagnostic tests are presented, and the role of different topical and systemic treatments is clearly described. The authors are world leaders in the field. The "Textbook of Hand Eczema" reflects a new era in hand dermatitis and will be invaluable for all who deal with the condition in their clinical practice.
10. 1. 1. 1 The Purpose of Patch Testing Patch testing is a well-established method of diagnosing allergic contact dermatitis, a delayed type of hypersensitivity (type IV reaction). Patients with a history and clinical picture of contact dermatitis are reexposed to the suspected allergens under controlled conditions to verify the diagnosis. Besides testing patients with hand, arm, face or leg eczema (stasis dermatitis), testing of other types of eczema (atopic, seborrhoeic dermatitis, nummular eczema) is sometimes indicated, especially when the dermatologist suspects contact allergy to prescribed topical medicaments and their vehicles. Apart from its use to confirm a suspected allergic contact dermatitis, the patch test procedure can also be used before recommending alternative corti costeroids, skin care products, cosmetics, gloves, etc. in a particular patient. If the patient does not react to the alternatives tested, it is very unlikely that she or he will react to the products in ordinary use. 10. 1. 1.2 Standardization The first patch tests according to present principles were carried out in 1895 [1], but were preceded by some preliminary experiments [2] (see Chap. 1).
The fifth edition delivers up-to-date coverage of every conceivable aspect in modern-day management of contact dermatitis. Leading experts have thoroughly updated the previous edition, while adding new chapters on genetics, the skin barrier, respiratory symptoms to chemicals and an extensive section on prevention. Both irritant and allergic contact dermatitis are covered with special emphasis on immunological mechanisms, molecular aspects of sensitizers, atypical clinical forms, reactions to medicaments, occupational and environmental aspects. The comprehensive yet approachable text is supplemented by numerous color illustrations and tables. Core messages and case reports highlight the most important information and help in gaining better understanding of the topic and greater competence in daily practice. An extensive dictionary of allergens gives quick access to specific information.
This book is a comprehensive but compact guide to the latest technical and technological developments in the growing field of non invasive diagnosis in clinical dermatology. Information is provided on the practical and technical characteristics of a wide range of equipment and methods for in vivo measurements that aid in the investigation of skin function, the evaluation of topically applied products and the monitoring of skin disease. Individual sections are devoted to imaging techniques, skin analysis, superficial skin analysis, skin mechanics, water and stratum corneum hydration and erythema and blood flow. All of the authors are experts in the field, with detailed knowledge of the techniques they describe. Non Invasive Diagnostic Techniques in Clinical Dermatology will be of value for all dermatologists, whether they are engaged in delivering patient care or in research programs, for cosmetic scientists and for biologists involved in skin research and product assessment.
First multi-year cumulation covers six years: 1965-70.