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Dermatotoxicology Methods
  • Language: en
  • Pages: 420

Dermatotoxicology Methods

  • Type: Book
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  • Published: 2019-05-07
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  • Publisher: CRC Press

This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.

DERMATOTOXICOLOGY 4ED
  • Language: en
  • Pages: 1962

DERMATOTOXICOLOGY 4ED

  • Type: Book
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  • Published: 1991-06-01
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  • Publisher: CRC Press

A guide to the field of dermatotoxicology. This edition includes fundamental information on the mechanisms of action of toxic substances on skin as well as practical information on the varied responses of skin to specific toxic substances and approaches to evaluating dermal toxicity. Other topics discussed include: hostile natural elements, such as ultraviolet radiation, poisonous plants, man-made detergents and chemicals; problems associated with chronic occupational skin exposure to toxic chemicals; animal alternative research programmes; carcinogenic and Photo Carcinogenic Potential Of Xenobiotic Chemicals; Oculotoxicity; Risk assessment and management; and cosmetic safety. Anatomical factors affecting barrier functions/ lipids of the permeability barrier/the skin immune system.

Handbook of Occupational Dermatology
  • Language: en
  • Pages: 1311

Handbook of Occupational Dermatology

A highly practical approach to occupational dermatoses combined with the skill and experience of specialists in clinical and experimental dermatology. Great care is taken throughout to provide the information urgently needed for daily patient management, with concise tables, algorithms, and figures on how to optimise the diagnostic procedure for high-quality patient care and expert opinion. This handbook provides the relevant job descriptions, job-specific diagnostic algorithms and a detailed description of allergens and irritants such that readers can master even difficult and unusual problems in occupational dermatology.

Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization
  • Language: en
  • Pages: 626

Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization

The new edition of this established and highly respected text is THE definitive reference in its field. It details methods for the elimination or prevention/control of microbial growth, and features: New chapters on bioterrorism and community healthcare New chapters on microbicide regulations in the EU, USA and Canada Latest material on microbial resistance to microbicides Updated material on new and emerging technologies, focusing on special problems in hospitals, dentistry and pharmaceutical practice Practical advice on problems of disinfection and antiseptics in healthcare A systematic review of sterilization methods, with uses and advantages outlined for each Evaluation of disinfectants and their mechanisms of action with respect to current regulations The differences between European and North American regulations are highlighted throughout, making this a truly global work, ideal for worldwide healthcare professionals working in infectious diseases and infection control.

Allergic Hypersensitivities Induced by Chemicals
  • Language: en
  • Pages: 366

Allergic Hypersensitivities Induced by Chemicals

  • Type: Book
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  • Published: 1995-11-27
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  • Publisher: CRC Press

This book, commissioned by the World Health Organization (WHO) and written by international experts, provides consensus views on the most important issues related to allergic hypersensitivities. The text details predictive testing, diagnosis, epidemiological monitoring of intervention measures, sources of sensitizing agents, and mechanisms of action. Contributors extensively cover allergic hypersensitivity reactions of the skin and the respiratory system. They present the current knowledge on hypersensitivity reactions of the gastrointestinal tract and kidneys. Major gaps in existing information about allergic hypersensitivities are highlighted and recommendations for future research are given. Practical methods are provided for establishing preventive programs. Allergic Hypersensitivities Induced by Chemicals offers valuable information to both scientists and public health officials. This is a useful reference for health professionals in their work with allergies, allergens, and allergy sufferers.

Hair in Toxicology
  • Language: en
  • Pages: 377

Hair in Toxicology

Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations. This authoritative book combines contributions from experts in academic, governmental and industrial environments, to provide a unique, comprehensive look at: - Why hair can serve as an invaluable bio-resource in toxicology, with up-to-date reviews on hair growth, hair fibre formation and hair pigmentation - Information (including regulatory details) on the exposure of hair (and by extension the body) to drug and non-drug chemicals and pollutants - Toxicological issues relevant to the use of...

Advances in Molecular Toxicology
  • Language: en
  • Pages: 286

Advances in Molecular Toxicology

  • Type: Book
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  • Published: 2010-06-28
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  • Publisher: Elsevier

Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Advan...

Profiles of Drug Substances, Excipients, and Related Methodology
  • Language: en
  • Pages: 514

Profiles of Drug Substances, Excipients, and Related Methodology

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. - Contributions from leading authorities - Informs and updates on all the latest developments in the field

Ergonomics In Computerized Offices
  • Language: en
  • Pages: 299

Ergonomics In Computerized Offices

  • Type: Book
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  • Published: 1986-12-18
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  • Publisher: CRC Press

"Ergonomics in Computerized Offices should be required reading for office managers, union representatives, engineers, designers, or anyone employed in implementing a computerized office or improving conditions in an already computerized office...an excellent addition to any personal library."--Human Factors Bulletin

Metalworking Fluids
  • Language: en
  • Pages: 508

Metalworking Fluids

  • Type: Book
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  • Published: 1994-06-14
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  • Publisher: CRC Press

This work provides concise introductory material on metallurgy for the novice, presenting up-to-date information on metalworking fluid technology. Its history, formulation, application, maintenance, testing and governmental regulation are detailed, and a trouble-shooting section is included on the causes of, and cures for, common industrial problems related to metalworking fluids.