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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. - Covers findings related to cardiovascular, inflammation, and pulmonary diseases - Examines issues in oncology, from mTor inhibitors to drug targets - Incorporates up-to-date information on drug design and discovery, including delivery to market
Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. In this first volume on Drug Transporters, the current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics are comprehensively reviewed. The second volume of the book is specifically dedicated to emerging science and technologies, highlighting potential areas for future advances within the drug transporter field. The topics covered in both volumes ensure that all relevant aspects of transporters are described across the drug development process, from in silico models and preclinical too...
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In 2004, the United States, five Central American countries, and the Dominican Republic signed the Central American Free Trade Agreement (CAFTA), signaling the region’s commitment to a neoliberal economic model. For many, however, neoliberalism had lost its luster as the new century dawned, and resistance movements began to gather force. Contesting Trade in Central America is the first book-length study of the debate over CAFTA, tracing the agreement’s drafting, its passage, and its aftermath across Central America. Rose J. Spalding draws on nearly two hundred interviews with representatives from government, business, civil society, and social movements to analyze the relationship betwee...
Launches an eight-volume series on the rebellious art form created during World War I by artists and writers in Zurich reacting to the horror of war, the onslaught of new technology, and the stifling aesthetics of futurism and cubism. In 11 essays, provides parameters for the historical and sociological context of the movement; its manifestation in visual arts, theater, the media, and literature; the correspondence between the actual works and the various manifestos; and the relevance of studying the phenomenon to present concerns. Illustrated in black and white. Annotation copyrighted by Book News, Inc., Portland, OR.
Published on the occasion of an exhibition organized by the National Museum of American Art and shown there Sept. 18, 1981-Jan. 3, 1982; at the Denver Art Museum, Jan. 23-Mar. 14, 1982; and at the Amon Carter Museum, May 7-July 4, 1982.
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