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Neon
The book endorses the National Science Foundation's concept of the National Ecological Observatory Network (NEON) for providing a nationwide network of facilities and infrastructure for ecological and environmental research that is impossible with existing infrastructure. The committee identified six grand challenges in environmental biology - biodiversity, biogeochemical cycles, climate change, ecology and evolution of infectious diseases, invasive species and land and habitat use-that deserves high priority for research and needs to be addressed on a regional or continental scale. However, the book says that NEON needs a refined focus and a more detailed plan for its implementation to ensure the maximization of its contribution to science and to better fit within the purview of Major Research Equipment and Facilities Construction funding.
Bacterial Pathogenesis of Plants and Animals
The last decade has seen an explosion in our understanding of how bacterial pathogens trick, cajole, usurp and parasitize their various hosts. This renaissance is due to the convergence of molecular and cellular techniques with the power of microbial genetics. The purpose of this volume is to introduce recent advances in understanding selected systems chosen from both plant and animal hosts of bacterial pathogens. This somewhat nonobvious choice of topics was spurred by the recent findings, detailed by several conributors to this volume, of common systems used to secrete virulence factors from pathogens of both plants and animals. These serendipitous findings underscored the importance of ba...
The Astrophysical Context of Life
In 1997, the National Aeronautics and Space Administration (NASA) formed the National Astrobiology Institute to coordinate and fund research into the origins, distribution, and fate of life in the universe. A 2002 NRC study of that program, Life in the Universe: An Assessment of U.S. and International Programs in Astrobiology, raised a number of concerns about the Astrobiology program. In particular, it concluded that areas of astrophysics related to the astronomical environment in which life arose on earth were not well represented in the program. In response to that finding, the Space Studies Board requested the original study committee, the Committee on the Origins and Evolution of Life, to examine ways to augment and integrate astronomy and astrophysics into the Astrobiology program. This report presents the results of that study. It provides a review of the earlier report and related efforts, a detailed examination of the elements of the astrobiology program that would benefit from greater integration and augmentation of astronomy and astrophysics, and an assessment of ways to facilitate the integration of astronomy with other astrobiology disciplines.
Enhancing the Vitality of the National Institutes of Health
The report says that important organizational changes are needed at the National Institutes of Health to ensure the agency meets future challenges effectively. In particular, the report advises NIH to devote additional resources to innovative interdisciplinary research that reflects its strategic objectives and cuts across all agency's institutes and centers. The report recommends that Congress should establish a formal process for determining how specific proposals for changes in the number of NIH agencies and centers should be addressed.
The Geological Record of Ecological Dynamics
In order to answer important questions about ecosystems and biodiversity, scientists can look to the past geological recordâ€"which includes fossils, sediment and ice cores, and tree rings. Because of recent advances in earth scientists' ability to analyze biological and environmental information from geological data, the National Science Foundation and the U.S. Geological Survey asked a National Research Council (NRC) committee to assess the scientific opportunities provided by the geologic record and recommend how scientists can take advantage of these opportunities for the nation's benefit. The committee identified three initiatives for future research to be developed over the next decade: (1) use the geological record as a "natural laboratory" to explore changes in living things under a range of past conditions, (2) use the record to better predict the response of biological systems to climate change, and (3) use geologic information to evaluate the effects of human and non-human factors on ecosystems. The committee also offered suggestions for improving the field through better training, improved databases, and additional funding.
The Role of Theory in Advancing 21st-Century Biology
Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.
Microbial Ecology in States of Health and Disease
Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may ...
Seeking Security
Within the last 30 years, the genomes of thousands of organisms, from viruses, to bacteria, to humans, have been sequenced or partially sequenced and deposited in databases freely accessible to scientists around the world. This information is accelerating scientists' ability to fight disease and make other medical advances, but policymakers must consider the possibility that the information could also be used for destructive purposes in acts of bioterrorism or war. Based in part on views from working biological scientists, the report concludes that current policies that allow scientists and the public unrestricted access to genome data on microbial pathogens should not be changed. Because access improves our ability to fight both bioterrorism and naturally occurring infectious diseases, security against bioterrorism is better served by policies that facilitate, not limit, the free flow of this information.
Ecological Impacts of Climate Change
The world's climate is changing, and it will continue to change throughout the 21st century and beyond. Rising temperatures, new precipitation patterns, and other changes are already affecting many aspects of human society and the natural world. In this book, the National Research Council provides a broad overview of the ecological impacts of climate change, and a series of examples of impacts of different kinds. The book was written as a basis for a forthcoming illustrated booklet, designed to provide the public with accurate scientific information on this important subject.
