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The Transcriptional Regulation of Memory
The formation of various forms of memory involves a series of distinct cellular and molecular mechanisms, many of which are not fully understood. There are highly conserved pathways that are involved in learning, memory, and synaptic plasticity, which is the primary substrate for memory storage. The formation of short-term (across minutes) memory is mediated by local changes in synapses, while long-term (across hours to days) memory storage is associated with activation of transcription and synthesis of proteins that modify synaptic function. Transcription factors, which can either repress or activate transcription, play a vital role in driving protein synthesis underlying synaptic plasticit...
Neuropsychology in the Care of People with Epilepsy
Having appeared in the 1930s in Montreal, standardised neuropsychological evaluation has become an essential tool in the clinical diagnosis and evaluation of surgical epileptic patients. Nevertheless, despite great progress over the last 20 to 30 years in the diagnosis and medical treatment of epilepsy, clinical neuropsychology still remains largely associated with surgical epilepsy, particularly surgery of the temporal lobe. Clinical neurology has still not managed to clear a way in the daily practice with patients with all types of epilepsy despite significant advances in cognitive neuroscience and a large number of clinical studies on epilepsy and cognition. How is it that there are only rarely major advances in the field of clinical neuropsychology? It has long been time for this question to be asked, and for an attempt to be made to bring about changes. This was the aim of the Toronto workshop and the result of this book. Every approach was debated, providing important elements to reflect on and allowing a great forum for exchanges. This book includes the communications from the main participants and comments from some others on specific subjects.
A Most Tolerant Little Town
"An intimate portrait of a small Southern town living through tumultuous times, this propulsive piece of forgotten civil rights history-about the first school to attempt court-ordered desegregation in the wake of Brown v. Board-will forever change how you think of the end of racial segregation in America. In graduate school, Rachel Martin volunteered with a Southern oral history project. One day, she was sent to a small town in Tennessee, in the foothills of the Appalachians, where locals wanted to build a museum to commemorate the events of August 1956, when Clinton High School became the first school in the former Confederacy to undergo court-mandated desegregation. After recording a dozen...
Epilepsy and Memory
Epilepsy is one of the most common potentially serious disorders of the brain, and patients often suffer from memory problems. This book comprehensively reviews all aspects of the relationship between this common and potentially serious neurological disorder and memory, one of the core functions of the human mind.
Olfaction and the Brain
Olfaction and its relation to mental health is an area of growing interest, evidenced by the 2004 Nobel Prize in Physiology or Medicine being awarded for discoveries relating to odorant receptors and the organization of the olfactory system. Olfaction is of particular interest to specialists seeking a fuller understanding of schizophrenia. Clear deficits in the sense of smell could predict schizophrenia in apparently unaffected individuals. In this book, first published in 2006, Warrick Brewer and his team of experts set out our understanding of olfaction and mental health, relating it to broader principles of neural development and processing as a foundation for understanding psychopathology. The neuropathological, neuropsychological and neuropsychiatric aspects of olfactory function and dysfunction are all covered (drawing on neuroimaging techniques where appropriate), and indications for future research and applications are discussed.
The Treatment of Epilepsy
A practical reference to the medical and surgicaltreatment of epilepsy The third edition of The Treatment of Epilepsy has beenthoroughly updated. It is a reference work, but has a strongpractical bias, and is designed to assist neurologists,neurosurgeons and other clinicians at all levels who are involvedin the treatment of patients with epilepsy. It is a definitivesource of clinical information to guide clinical practice andrational therapy. Written and edited by leading experts, many actively involvedwith the International League Against Epilepsy, this newedition: covers the recent advances in the principles and approaches toepilepsy therapy, the introduction of new drugs and the developmentof new surgical techniques contains 26 completely new chapters and 61 newcontributors includes pharmacological properties and prescribing informationfor all drugs used in the treatment of epilepsy features the important contribution of a new editor JeromeEngel Jr, Professor of Neurology at the University of CaliforniaSchool of Medicine in Los Angeles.
The Dalai Lama at MIT
Their meeting captured headlines; the waiting list for tickets was nearly 2000 names long. If you were unable to attend, this book will take you there. Including both the papers given at the conference, and the animated discussion and debate that followed, The Dalai Lama at MIT reveals scientists and monks reaching across a cultural divide, to share insights, studies, and enduring questions. Is there any substance to monksÕ claims that meditation can provide astonishing memories for words and images? Is there any neuroscientific evidence that meditation will help you pay attention, think better, control and even eliminate negative emotions? Are Buddhists right to make compassion a fundamental human emotion, and Western scientists wrong to have neglected it? The Dalai Lama at MIT shows scientists finding startling support for some Buddhist claims, Buddhists eager to participate in neuroscientific experiments, as well as misunderstandings and laughter. Those in white coats and those in orange robes agree that joining forces could bring new light to the study of human minds.
NeuroPhytomedicine
Neurological disorders categorized as neurodegenerative, neuropsychiatric, and neurotraumatic impose a substantial health burden and cause a frail impact on life attributes. The use of synthetic drugs can have undesirable side effects, making neurotherapeutics challenging. Research on neuroprotection aiming for the utilization of safer natural compounds; phytochemicals specifically – is a cutting-edge approach. NeuroPhytomedicine intends to present readers with a wide-ranging and state-of-the-art appearance at the beneficial properties of phytochemicals on various neurological ailments. It additionally contains sections explaining: • Applications of phyto-nanotechnology in neurological ailments, • Phytoconstituents related deep learning and machine learning-based solutions for neurological disorders, • Epigenetic relevance pertaining to modulation by phytochemicals. The goal of NeuroPhytomedicine is to give readers a thorough and up-to-date look at how phytochemicals affect the brain and neurological illnesses in a way that is helpful for research scholars, academicians, scientists, neuroscientists, physicians, and researchers from the pharmaceutical industry.
How to Speak Human
'An instant classic—this book is so utterly relevant and needed. And it is hellishly refreshing to boot. I fucking love it, and heartily recommend it to all.' —Dr Jason Fox, best-selling author of How to Lead a Quest Take a practical approach to the communication challenges in your workplace. Through 11 strategies, 23 tactics and 15 stories this handy how-to will help curious humans: use the science of connection to create compelling communication translate mind-numbing complexity into captivating simplicity hijack attention, engage and influence others. Whether you're a leader looking to connect with your workforce; a member of a small team, hungry to make a difference; or at the helm of a global organisation, with an eye on the horizon – this is a how-to for forward thinkers like you.
Human Trafficking, Human Security, and the Balkans
In the aftermath of four Yugoslav wars, ongoing efforts at reconstruction in South Eastern Europe have devoted relatively limited attention to dimensions of human security that enhance protections for the region's most vulnerable populations in their daily lives. It is in this context that South Eastern Europe, and especially the Western Balkan region, has emerged as a nexus point in human trafficking.Human Trafficking, Human Security, and the Balkans brings together leading scholars, NGO representatives, and government officials to analyze and offer solutions to this challenge. The contributors explore the economic dynamics of human trafficking in an era of globalization, which has greatly facilitated not only the flow of goods and services but also the trade in human beings. They also examine the effectiveness of international and transnational policies and practice, the impact of peacekeeping forces, and the emergence of national and regional action plans in the Western Balkans and, more broadly, in South Eastern Europe. Finally, they consider the nature and ramifications of the gap between human security rhetoric and institutional policy steps against human trafficking.
