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Proteomic and Genomic Analysis of Cardiovascular Disease
This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the various strategies and technical aspects so as to assist the growing number of researchers intending to utilize these approaches. The result is an excellent way of educating and informing graduate students, post-doctoral fellows as well as researchers in academia and industry about the latest developments in this area.
Clinical Proteomics
Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.
Cardiovascular Proteomics
This cutting-edge book presents protocols and strategies for proteomic evaluation of cardiovascular disease written by pioneering researchers in the field. Topics explored in this comprehensive volume include obtaining specific heart proteins, techniques for identifying risk biomarkers of atherome plaque rupture, analyzing the secretome of explanted endarterectomies cultured in vitro, and phage display techniques for deciphering the molecular diversity of blood vessels.
Cardiac Arrest
Cardiac Arrest is the definitive and most comprehensive reference in advanced life support and resuscitation medicine. This new edition brings the reader completely up-to-date with developments in the field, focusing on practical issues of decision making, clinical management and prevention, as well as providing clear explanations of the science informing the practice. The coverage includes information on the latest pharmacotherapeutic options, the latest chest compression techniques and airway management protocols, all backed by clearly explained, evidence-based scientific research. The content is consistent with the latest guidelines for practice in this area, as detailed by the major international governing organisations. This volume is essential reading for all those working in the hospital environments of emergency medicine, critical care, cardiology and anesthesia, as well as those providing care in the pre-hospital setting, including paramedics and other staff from the emergency services.
Cardiovascular Biomarkers
In the four pages committed to a discussion of myocardial infarction in the first edition of Harrison’s Principles of Internal Medicine, published in 1950, there was no mention of use of the laboratory for management of patients. Thirty years later, when the first edition of Braunwald’s Heart Disease, A Textbook of Cardiovascular Medicine was published, 2 out of the 1943 pages in the text contained a discussion of the laboratory examinations in acute myocardial infarction. Our knowledge base of the multitude of ways that physicians can and should use the clinical chemistry laboratory has expanded dramatically since these classic texts were published. The nomenclature has changed: terms s...
Muscle 2-Volume Set
Muscle: Fundamental Biology and Mechanisms of Disease will be the first reference covering cardiac, skeletal, and smooth muscle in fundamental, basic science, translational biology, disease mechanism, and therapeutics. Currently there are no publications covering the science behind the medicine, as the majority of books are 90% clinical and 10% science. Muscle: Fundamental Biology and Mechanisms of Disease will discuss myocyte biology, also known as muscle cell biology, providing information about the science behind clinical work and therapeutics with a 90% science and 10% clinical focus. A needed resource for researchers, clinical professionals, postdocs, and graduate students, this publication will further discuss basic biology development and physiology, how processes go awry in disease states, and how the defective pathways are targeted for therapy. This book will assist both the new and experienced clinician's and researcher's need for science translation of background research into clinical applications, bridging the gap between research and clinical knowledge.
Bioinformatics
An emerging, ever-evolving branch of science, bioinformatics has paved the way for the explosive growth in the distribution of biological information to a variety of biological databases, including the National Center for Biotechnology Information. For growth to continue in this field, biologists must obtain basic computer skills while computer spe
AHA Scientific Sessions 2019 - Final Program
The American Heart Association’s Scientific Sessions 2019 is bringing big science, big technology, and big networking opportunities to Philadelphia, Pennsylvania this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
Atherosclerosis
Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics. Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy analyses recent progress from both conceptual and technological perspectives, suggesting new directions for atherosclerosis research and treatment for a growing population of researchers and clinicians in cardiovascular and related fields.
Cardiac Markers
In this greatly enlarged and thoroughly updated edition of his much praised Cardiac Markers, Alan Wu and his contributors focus on the use of markers in the practice of cardiology and-for the first time-on the use of natriuretic peptides for congestive heart failure. Here, leading international authorities in clinical chemistry and laboratory medicine, cardiology, emergency medicine, and the in vitro diagnostics industry describe the state-of-the-art uses of cardiac markers when treating coronary artery disease, and discuss in detail how they may be optimally used in a clinical setting. Comprehensive and cutting-edge, Cardiac Markers, Second Edition offers physicians a complete guide to the use of cardiac markers in clinical practice and clinical laboratorians a close-up view of the new markers now becoming standard.
