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Biological Aging
This book investigates the various processes that are affected by the age of an organism. Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions.
Oxidative Stress and Age-Related Neurodegeneration
Oxidative Stress and Age-Related Neurodegeneration brings together researchers from a variety of fields to compare normal aging and disease-related neurodegeneration in terms of susceptibility to and effects of oxidative stress. They address how these effects can be attenuated, and examine whether antioxidants and natural micronutrients, such as those found in Gingko biloba, green tea, blueberries, and grape seed extract, can play a role. The book includes various ways research is getting to the core of neurodegenerative disease, including the use of proteomics, comparisons to related diseases, and examinations at the cellular and molecular levels.
Gene Therapy
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. Volume 40, GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and more.Key Features* It provides an excellent overview on a series of topics on gene therapy for the serious investigator
Combinational Immunotherapy of Cancer: Novel Targets, Mechanisms, and Strategies
Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manip...
Ovarian Cancer
This reference details recent knowledge of ovarian cancer. Areas covered include: the genetic basis and molecular biology of ovarian cancer, analytic approaches to diagnosis and management, experimental therapeutics - gene therapy, methodology for dose intensification, new drugs, and quality of life and ethical issues.
Proceedings of 8th Molecular Immunology & Immunogenetics Congress 2017
March 20-21, 2017 Rome, Italy Key Topics : Immuno Genetics & Histocompatibility, Molecular Immunology, Cellular Immunology, Tumor Immunology, Auto Immune Diseases, Vaccinology, Haematopoietic and Lymphoid Malignancies, Immunoproliferative disorders, Paediatric Immunology, Immunodermatology, Osteoimmunology, Immunohaematology, Transplantation Immunology, Cellular Therapy, Immunological Techniques, Microbial Immunology, Industrial Immunology, Computational Immunology, Cancer Immunology, Biochemistry and Molecular Biology, Molecular Medicine, Clinical and Molecular Allergy, Molecular Biomarker, Molecular & Cellular Oncology,
