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Probing Intracellular Regulation
Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science is an e-book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essentiality and diversity of genomics in contemporary science. The second volume of this ebook series contains a selection of articles on intracellular gene regulation and expression in human disease such as arthritis, Alzheimer’s disease, Nijmegen Breakage Syndrome, Tumors and Malaria among other diseases. The volume also features some chapters on plant genetics
Genetic Polymorphisms
This book provides a glimpse into the dynamic process of genetic polymorphism by presenting studies carried out on different kinds of organisms at the DNA level or gene expression level. Chapters address such topics as genetic polymorphism in animals, gametocyte biomarkers, thrombotic disorders, prostate cancer, and more.
Landscapes of Disease
Malaria has existed in Greece since prehistoric times. Its prevalence fluctuated depending on climatic, socioeconomic and political changes. The book focuses on the factors that contributed to the spreading of the disease in the years between independent statehood in 1830 and the elimination of malaria in the 1970s. By the nineteenth century, Greece was the most malarious country in Europe and the one most heavily infected with its lethal form, falciparum malaria. Owing to pressures on the environment from economic development, agrarian colonization and heightened mobility, the situation became so serious that malaria became a routine part of everyday life for practically all Greek families,...
Diseases and Human Evolution
Urgent interest in new diseases, such as the coronavirus, and the resurgence of older diseases like tuberculosis has fostered questions about the history of human infectious diseases. How did they evolve? Where did they originate? What natural factors have stalled the progression of diseases or made them possible? How does a microorganism become a pathogen? How have infectious diseases changed through time? What can we do to control their occurrence? ; Ethne Barnes offers answers to these questions, using information from history and medicine as well as from anthropology. She focuses on changes in the patterns of human behavior through cultural evolution and how they have affected the develo...
Plagues and the Paradox of Progress
Why the news about the global decline of infectious diseases is not all good. Plagues and parasites have played a central role in world affairs, shaping the evolution of the modern state, the growth of cities, and the disparate fortunes of national economies. This book tells that story, but it is not about the resurgence of pestilence. It is the story of its decline. For the first time in recorded history, virus, bacteria, and other infectious diseases are not the leading cause of death or disability in any region of the world. People are living longer, and fewer mothers are giving birth to many children in the hopes that some might survive. And yet, the news is not all good. Recent reductio...
Medicine and Health in Africa
Over the last two decades, the implosion of economies under the burden of debt, the negative repercussions of structural adjustment programs, the crisis of legitimacy, civil wars, and the collapse of some states have resulted in serious health issues across the African continent. Newly emerging diseases, such as Ebola virus and HIV/AIDS have killed and disabled millions. Some “old diseases,” such as yellow fever, tuberculosis, and polio have reappeared. Malaria, cholera, and meningitis continue to kill thousands. In many countries, the medical infrastructure has collapsed, while an increasing number of physicians and nurses have migrated to more hospitable places. Stigmatization of the affected people has exacerbated social and racial discrimination and has affected the implementation of national and international public health programs. The complexity of the situation requires an interdisciplinary approach. This collection, including contributions by historians, sociologists, anthropologists, and biologists, emphasizes the social and cultural contexts of African health, paying particular attention to the history of the colonial public health system and its legacy.
Globalization, Health, and the Environment
Leading health scholars reveal the impact of globalization on human health, as it is mediated through environmental change. They explore the destabilizing impact of globalization on the planet's ecology, and on the health of the human populations that are dependent on the delicate global bionetwork. Their timely case studies describe the cultural adaptations of indigenous populations to their changing environments, evaluating their technological and global political-economic processes. The authors analyze local and global public health strategies, examine the association between globalization and demographies, and offer creative solutions for future health policies. This book will be a valuable resource for professionals in international health, medical anthropology, sociology and geography, environmental studies, and globalization studies.
