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Neuropeptides and Brain Function
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Endogenous Peptides and Learning and Memory Processes presents the role of pituitary and central nervous system peptidergic systems in the modulation of memory and learning. This book discusses the various experimental findings concerning the role of peptides in attention, memory, conditioning, opiate tolerance, and amnesia. Organized into five parts encompassing 26 chapters, this book starts with an overview of the possible chemical relationship between melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). This text then discusses the complex behavioral activities of ACTH involving processes that serve the adaptive abilities of the organism, such as memory, learning, ...
Advances in Pharmacology and Therapeutics II, Volume 1: CNS Pharmacology Neuropeptides contains the proceedings of the Eighth International Congress of Pharmacology held in Tokyo in 1981. This book is the first of a six-volume compilation of the scientific papers of invited speakers. Separating 26 papers as chapters, this book begins with an invited lecture on opioid peptides and their receptors. Other chapters describe opioid peptides and their relevance to central nervous system mechanisms; neuropeptides and related compounds affecting learning and memory; and pharmacological approaches to the study of sleep regulation. This book also explores the importance of kainic acid and related compounds as a pharmacological tool.
Over the last decade the world has experienced a growing interest in problems associated with the nonmedical use of drugs. This interest has corresponded to a real growth in the extent, diversity, and social impact of the use of alcohol and drugs in many societies. As a result, the amount of research and writing on the subject of drug problems has greatly increased, and it has become very difficult for one individual to keep up with all the relevant literature. There is thus an acute need in the field for critical reviews that assess current developments, and the present series is intended to fill this need. The series is not to be an "annual review" in the usual sense. The aim is not to cov...
The Human Hypothalamus in Health and Disease
Latest issue in the CURRENT TOPICS IN NEUROENDOCRINOLOGY se- ries which has been gaining a great deal of reputation as a primary source for reviews in neuroendocrinology and related areas in the past few years.
On the occasion of David de Wied's retirement as Professor of Pharmacology and Chairman of the Board of the Rudolf Magnus Institute, it was thought to be the appropriate moment to publish a volume reviewing the state-of-the-art concept on neuropeptide research. A major part of this research originated from De Wied, and the authors who contributed to the volume are all former or current associates. The volume begins with a classic article written by David de Wied in the late 1960's, which pointed the direction on which twenty years of multidisciplinary research could be based. Further chapters include aspects such as central neurohypophyseal hormone receptors and receptor mediated cellular responses, neuropeptides and behavioral adaptation: structure-activity relationships, neuro-opioid peptides and blood pressure control, neuropeptides and brain aging.
This book is presented as a 1989 update on the task set by Robert Burton in his "Anatomy ofMelancholy," published in 1621. Burton's treatise addressed ques tions regarding depression which are still highly relevant today: ." . . What is it, with all the kinds, causes, symptoms, prognostickes and several cures ofit. . . . " These remain the core issues in affective disorders notwithstanding the remarkable progress that has been made in addressing them. New Directions in Affective Disorders sets out to provide an overviewofwhat has been achieved with particular emphasison developing trends and novel initiatives in bothfundamental research and treatment. The overriding objective of the book is ...
The 39 chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment. The aim is to integrate pertinent information from the fields of molecular and cell biology with view to establishing a molecular basis of alcohol use and abuse. An initial preview summarizes historical aspects of alcohol use, and subsequent chapters concern novel drugs, pharmacological aspects, gene structures, cloning, and enzymatic properties. Also contributions by "non-traditional" alcohol scientists have been included in this collection, in order to highlight possible interaction and parallels between different fields. Novel results of particular interest include up-dated summaries on receptors, enzymes, and other proteins, as well as corresponding gene structures and regulation, setting the basis for distinguishing markers and pinpointing further possible pharmacological treatments.