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Comorbidities in Chronic Kidney Disease (CKD)
With a mean worldwide prevalence of 13%, chronic kidney disease imposes a massive health burden on our society. In addition to reduced kidney function, patients with chronic kidney disease increasingly suffer from cardiovascular diseases affecting the heart and vasculature. Cardiovascular diseases account for around half of the deaths of patients with advanced chronic kidney disease. However, therapeutic options are highly insufficient. The pathological mechanisms that underlie increased cardiovascular risk in patients with chronic kidney disease remain largely unknown. This Special Issue provides insights into comorbidities in CKD patients, mainly focused on increased cardiovascular risk, and summarizes current knowledge of underlying pathophysiological mechanisms.
Integration of Omics Approaches and Systems Biology for Clinical Applications
Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape o...
Uremic Toxins
Reviews all the latest basic and clinical research findings With contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices. Uremic Toxins is divided into three sections: Section One, Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxins Section Two, Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plas...
Platelets and Megakaryocytes
12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are, however, far from understanding precisely how platelets become activated under physiological and pathophysiological conditions. In addition, there are large gaps in our knowledge of platelet production from their giant precursor cell, the megakar- cyte. Understanding megakaryocyte biology will be crucial for the development of platelet gene targeting. The aim...
Protein Liquid Chromatography
Protein Liquid Chromatography is a handbook-style guide to liquid chromatography as a tool for isolating and purifying proteins, consisting of 25 individual chapters divided into three parts: Part A covers commonly-used, classic modes of chromatography such as ion-exchange, size-exclusion, and reversed-phase; Part B deals with various target protein classes such as membrane proteins, recombinant proteins, and glycoproteins; and Part C looks at various miscellaneous related topics, including coupling reaction, buffer solution additives, and software. The text as a whole can be viewed as a systematic survey of available methods and how best to use them, but also attempts to provide an exhausti...
Vascular Biology, Haemostasis and Extracellular Nucleic Acids in Vascular Diseases and Immunity. A Tribute to Klaus T. Preissner
Topic Editor Prof. Ritva Tikkanen Receives Research Funding From Neurogene Inc. and GC Pharma for Studies Unrelated to the Subject. Topic Editor Prof. Carl Blobel is Co-Inventor on a Patent Describing a Method of Identifying Agents for Combination With Inhibitors of iRhoms. He and the Hospital for Special Surgery (New York, USA) are Investigating Suitable Approaches to Identify iRhom Inhibitors, and are Co-Founders of a Small Company Called SciRhom in Munich to Pursue These Efforts. Topic Editor Dr. Sylvia Fischer Declares no Competing Interests With Regards to the Research Topic Subject.
Chronic Kidney Disease For Everyone
This ebook provides simple, easy to understand information regarding the topic of chronic kidney disease. It explains the causes of this problem, the mechanism of disease, the treatment options and the prognosis.
Diabetes
The book explains the underlying pathophysiology of the disease and covers in detail all its main forms and complications. Separate chapters consider the range of treatment options, together with summaries of key clinical trials. Coverage also includes epidemiology and classification, as well as diagnosis, screening, limiting risk, and other aspects of disease management and patient care. The book is illustrated throughout by explanatory diagrams, graphs, tables, and photos. Key Features: 1. Builds on its strength of having excellent content on long-term management of hyperglycemia by including pancreas and islet transplantation. 2. Contains invaluable information on glucose monitoring for healthcare professionals interested in diabetes.
World Congress on Medical Physics and Biomedical Engineering 2018
This book (vol. 3) presents the proceedings of the IUPESM World Congress on Biomedical Engineering and Medical Physics, a triennially organized joint meeting of medical physicists, biomedical engineers and adjoining health care professionals. Besides the purely scientific and technological topics, the 2018 Congress will also focus on other aspects of professional involvement in health care, such as education and training, accreditation and certification, health technology assessment and patient safety. The IUPESM meeting is an important forum for medical physicists and biomedical engineers in medicine and healthcare learn and share knowledge, and discuss the latest research outcomes and technological advancements as well as new ideas in both medical physics and biomedical engineering field.
