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This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.
In RFD #3, Harry Wayne Addison, an eloquent spokesman of his rural north Louisiana heritage, addresses many of that tradition's values, their importance to his life, and their application to a broad range of human relationships. Perhaps north Louisiana's premier native-born humorist, Addison is renowned throughout the area as a gifted after-dinner speaker, annually making some seventy-five appearances throughout Louisiana, Arkansas, and Mississippi. In this volume, Addison comments wittily, often wryly, and always perceptively about incidents, events, and character-building circumstances of his rural upbringing. The title of this book is derived from one such anecdote. Nostalgic in tone and ...