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Emphasizes the importance of early intervention in RA with focus on pharmacologic treatment of RA. Detailed information on the various medications employed in treatment, including corticosteroids, NSAIDs DMARDs, biologic agents, and combination therapy is reviewed, including evidence based data on efficacy, safety, side effects, and monitoring requirements. Clinical evaluation is presented, including lab findings, joint scoring, diagnostic criteria, and radiographic outcomes. Surgical options and the management of advanced RA are disussed.
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Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path
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A clinically oriented, user-friendly text on the diagnosis and treatment of infectious diseases for practising clinicians, students and residents.
Leukocyte adhesion molecules have been the subject of intense basic and preclinical research. Results from clinical trials obtained sofar with antibodies directed towards these surface proteins offer promise for the prevention of graft rejection and effective treatment of acute and chronic inflammatory disease. This volume presents a comprehensive review of contemporary research on the structure, function and regulation of leukocyte adhesion molecules and their ligands, from the molecular to the clinical level. The blend of basic science and clinical applications presented in Structure, Function and Regulation of Molecules Involved in Leukocyte Adhesion provides clear evidence of the biological importance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion. It will appeal to a broad range of readers in immunology and cell biology.
Clinical Primer of Rheumatology is designed as a concise, essential reference to aid practitioners in diagnosing and treating rheumatoid diseases. More than 200 photographs and many tables and charts provide easy access to information necessary to identify the cause of a patient's complaint and plan a course of therapy. Recommendations on when to refer a patient to a specialist are clearly indicated in the text. Comprehensive coverage of specific rheumatoid diseases is included along with information on sports and occupational-related pain syndromes.
Provides a detailed survey of therapies for autoimmune diseases, exploring the rationale for their use and clinical data regarding their potential benefit.
Rheumatology--with all the authority of HARRISON'S Featuring the chapters on rheumatology that appear in Harrison's Principles of Internal Medicine, 17e, this compact clinical companion delivers the latest knowledge in the field, backed by the scientific rigor and reliability that have defined Harrison's. Inside you'll find coverage that reflects the expertise of renowned editors and contributors--presented in a carry-anywhere format that makes it ideal for the classroom, the wards, or exam/certification preparation. Features: Current, thorough coverage of need-to-know immunology and rheumatology topics, including the immune system in health and disease, disorders of immune-mediated injuries...