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Autoimmunity
  • Language: en
  • Pages: 432

Autoimmunity

“Research is to see what everybody else has seen, and to think what nobody else has thought. ” — Albert Szentgyörgyi Autoimmunity: Methods and Protocols is intended to serve as a ready-to-use guide to establish and interrogate human and animal models of autoimmune diseases. The first chapter, “Pathogenesis and Spectrum of Autoimmunity,” discusses major hypotheses driving this most tantalizing area of research since Paul Ehrlich proposed the concept of autoimmunity in 1900. Considering the great diversity and ever-changing spectrum of autoimmunity, it has not been possible to include models and experimental protocols for each known disorder. Rather, several chapters have been devot...

Current Medicinal Chemistry
  • Language: en
  • Pages: 100

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1998-12
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  • Publisher: Unknown

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Current Medicinal Chemistry
  • Language: en
  • Pages: 82

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1997-12
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  • Publisher: Unknown

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Molecular Cardiology
  • Language: en
  • Pages: 410

Molecular Cardiology

The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the...

Current Medicinal Chemistry
  • Language: en
  • Pages: 148

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1999-08
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  • Publisher: Unknown

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Pancreatic Cancer
  • Language: en
  • Pages: 350

Pancreatic Cancer

Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer death in the United States. Annually approximately 30,000 Americans are diagnosed with the disease and most will die from it within five years. P- creatic ductal adenocarcinoma is unique because of its late onset in age, high mortality, small tumor samples infiltrated with normal cells, and a lack of both early detection and effective therapies. Some of these characteristics have made studying this disease a challenge. Pancreatic cancer develops as a result of the accumulation of genetic alterations in cancer-causing genes, such as the oncogenes and the tumor-s- pressor genes. In the last decade, major progress has been m...

Current Medicinal Chemistry
  • Language: en
  • Pages: 94

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1999-04
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  • Publisher: Unknown

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Current Medicinal Chemistry
  • Language: en
  • Pages: 76

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1998-02
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  • Publisher: Unknown

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Current Medicinal Chemistry
  • Language: en
  • Pages: 140

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1999-09
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  • Publisher: Unknown

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Current Medicinal Chemistry
  • Language: en
  • Pages: 114

Current Medicinal Chemistry

  • Type: Magazine
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  • Published: 1999-11
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  • Publisher: Unknown

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